Results 31 to 40 of about 340,714 (313)

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

FEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung, Mikhail G. Dozmorov, SuJeong Song, Theingi Aung, Min Hee Park, Patricia J. Sime, Wook‐Jin Chae   +6 more
wiley   +1 more source

Resveratrol Modulates Desaturase Expression and Fatty Acid Composition of Cultured Hepatocytes

Frontiers in Nutrition, 2018
This study aimed to evaluate whether resveratrol (RSV) and its microbial metabolites dihydro-resveratrol (DHR) and lunularin (LUN) affected fatty acid metabolism and omega-3 polyunsaturated fatty acid (n3-PUFA) synthesis in cultured hepatocytes.
Gianna Kühn, Kathrin Pallauf, Carsten Schulz, Carsten Schulz, Marc Birringer, Beatriz Diaz-Rica, Sonia de Pascual-Teresa, Gerald Rimbach   +7 more
doaj   +1 more source

Self-Assembled Fatty Acid Crystalline Coatings Display Non-Toxic Superhydrophobic Antimicrobial Properties [PDF]

arXiv, 2022
Superhydrophobcity is a well-known wetting phenomenon found in numerous plants and insects. It is achieved by the combination of the surfaces chemical properties and its surface roughness. Inspired by nature, numerous synthetic superhydrophobic surfaces have been developed for various applications.
arxiv  

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

FEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga, Kazuki Harada, Takuya Yamauchi, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi   +6 more
wiley   +1 more source

Low-temperature effects on docosahexaenoic acid biosynthesis in Schizochytrium sp. TIO01 and its proposed underlying mechanism

Biotechnology for Biofuels, 2020
Background Schizochytrium species are known for their abundant production of docosahexaenoic acid (DHA). Low temperatures can promote the biosynthesis of polyunsaturated fatty acids (PUFAs) in many species. This study investigates low-temperature effects
Fan Hu, April L. Clevenger, Peng Zheng, Qiongye Huang, Zhaokai Wang   +4 more
doaj   +1 more source

Disrupting the Acyl Carrier Protein/SpoT interaction in vivo: identification of ACP residues involved in the interaction and consequence on growth. [PDF]

PLoS ONE, 2012
In bacteria, Acyl Carrier Protein (ACP) is the central cofactor for fatty acid biosynthesis. It carries the acyl chain in elongation and must therefore interact successively with all the enzymes of this pathway.
Sandra Angelini, Laetitia My, Emmanuelle Bouveret   +2 more
doaj   +1 more source

Sensitive methods for estimating the anchoring strength of nematic liquid crystals on Langmuir-Blodgett monolayers of fatty acids [PDF]

, 2000
The anchoring of the nematic liquid crystal N-(p-methoxybenzylidene)-p-butylaniline (MBBA) on Langmuir-Blodgett monolayers of fatty acids (COOHC$_{n}$H$_{2n+1}$) was studied as a function of the length of the fatty acid alkyl chains, $n$ ($n = 15, 17, 19, 21$).
arxiv   +1 more source

Fatty Acid Synthesis by Extracts of Euglena [PDF]

Plant Physiology, 1965
At least 3 known pathways are available to a cell to synithesize satuirated fatty acids: A) the malonylCoA pathwav which has been shown to result in do novo synthesis of long-chain fatty acids, B) reversal of the fl-oxidation pathway which results primarily in syinthesis of short-chain acids and onlv negligible amounlits of long-chain fatty acids.
Pat Carey Kerr, George M. Cheniae
openaire   +3 more sources

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

FEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva, Marcio Vinicius Bertacine Dias   +1 more
wiley   +1 more source

The Regulation of Fatty Acid Synthesis in Human Skin Fibroblasts

Journal of Biological Chemistry, 1973
Abstract The short term regulation of fatty acid biosynthesis has been studied using primary cultures of human skin fibroblasts. These cells show rapid changes in rates of acetate incorporation into fatty acids depending upon the lipid content of the medium.
Philip W. Majerus, Richard A. Jacobs
openaire   +3 more sources