Journal of Lipid Research, 1966 Effects of prolonged ingestion of glucose and ethanol on the rate of fatty acid synthesis by liver and adipose tissue have been investigated in male rats.
Nicholas M. Alexander +2 more
doaj +1 more source
FADS Gene Cluster Polymorphisms: Important Modulators of Fatty Acid Levels and Their Impact on Atopic Diseases [PDF]
, 2009 Long-chain polyunsaturated fatty acids (LC-PUFAs) play an important role in several physiological processes and their concentration in phospholipids has been associated with several complex diseases, such as atopic disease.
Heinrich, Joachim +3 more
core +1 more source
Mechanisms Mediating the Regulation of Peroxisomal Fatty Acid Beta-Oxidation by PPARα
International Journal of Molecular Sciences, 2021 In mammalian cells, two cellular organelles, mitochondria and peroxisomes, share the ability to degrade fatty acid chains. Although each organelle harbors its own fatty acid β-oxidation pathway, a distinct mitochondrial system feeds the oxidative ...
Mounia Tahri-Joutey +5 more
semanticscholar +1 more source
Post-heparin phospholipase and fatty acid transesterification in human plasma
Journal of Lipid Research, 1965 The incubation of post-heparin plasma and egg phosphatidyl ethanolamine in the presence of methanol, ethanol, or glycerol resulted in the synthesis of fatty acid esters of these alcohols.
William C. Vogel +3 more
doaj +1 more source
The diversity and breadth of cancer cell fatty acid metabolism
Cancer & Metabolism, 2021 Tumor cellular metabolism exhibits distinguishing features that collectively enhance biomass synthesis while maintaining redox balance and cellular homeostasis.
Shilpa R. Nagarajan, L. Butler, A. Hoy
semanticscholar +1 more source
Foods, 2023 The synthesis of tea fatty acids plays a crucial role in determining the oil content of tea seeds and selecting tea tree varieties suitable for harvesting both leaves and fruits.
Li Jiang +11 more
doaj +1 more source
Histone demethylase JMJD1C is phosphorylated by mTOR to activate de novo lipogenesis. [PDF]
, 2020 Fatty acid and triglyceride synthesis increases greatly in response to feeding and insulin. This lipogenic induction involves coordinate transcriptional activation of various enzymes in lipogenic pathway, including fatty acid synthase and glycerol-3 ...
Choi, Yoon +4 more
core
Myristic acid potentiates palmitic acid-induced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis. [PDF]
, 2015 Palmitic acid (PA) induces hepatocyte apoptosis and fuels de novo ceramide synthesis in the endoplasmic reticulum (ER). Myristic acid (MA), a free fatty acid highly abundant in copra/palmist oils, is a predictor of nonalcoholic steatohepatitis (NASH) and
Alarcón-Vila, C +9 more
core +2 more sources
Withania somnifera root extract inhibits fatty acid synthesis in prostate cancer cells
Journal of Traditional and Complementary Medicine, 2020 Prior research argues for a role of increased de novo fatty acid synthesis in pathogenesis of prostate adenocarcinoma, which remains a leading cause of cancer-associated mortality in American men. A safe and effective inhibitor of fatty acid synthesis is
Su-Hyeong Kim +4 more
doaj +1 more source
Dysregulated Choline, Methionine, and Aromatic Amino Acid Metabolism in Patients with Wilson Disease: Exploratory Metabolomic Profiling and Implications for Hepatic and Neurologic Phenotypes. [PDF]
, 2019 Wilson disease (WD) is a genetic copper overload condition characterized by hepatic and neuropsychiatric symptoms with a not well-understood pathogenesis.
Czlonkowska, Anna +6 more
core +2 more sources