Results 61 to 70 of about 619,233 (330)

The cytochrome oxidase defect in ISC‐depleted yeast is caused by impaired iron–sulfur cluster maturation of the mitoribosome assembly factor Rsm22

FEBS Letters, EarlyView.
The yeast mitoribosome assembly factor Rsm22 contains a [4Fe‐4S] cluster that is matured by the mitochondrial iron–sulfur cluster assembly (ISC) machinery. Defects in ISC components result in impaired mitochondrial protein synthesis due to a mitoribosome assembly defect.
Ulrich Mühlenhoff, Dominik Trauth, Weronika Śliwińska, Linda Boss, Roland Lill   +4 more
wiley   +1 more source

Differential Reliance on Lipid Metabolism as a Salvage Pathway Underlies Functional Differences of T Cell Subsets in Poor Nutrient Environments

Cell Reports, 2018
Summary: T cells compete with malignant cells for limited nutrients within the solid tumor microenvironment. We found that effector memory CD4 T cells respond distinctly from other T cell subsets to limiting glucose and can maintain high levels of ...
Christopher Ecker, Lili Guo, Stefana Voicu, Luis Gil-de-Gómez, Andrew Medvec, Luis Cortina, Jackie Pajda, Melanie Andolina, Maria Torres-Castillo, Jennifer L. Donato, Sarya Mansour, Evan R. Zynda, Pei-Yi Lin, Angel Varela-Rohena, Ian A. Blair, James L. Riley   +15 more
doaj   +1 more source

Low-temperature effects on docosahexaenoic acid biosynthesis in Schizochytrium sp. TIO01 and its proposed underlying mechanism

Biotechnology for Biofuels, 2020
Background Schizochytrium species are known for their abundant production of docosahexaenoic acid (DHA). Low temperatures can promote the biosynthesis of polyunsaturated fatty acids (PUFAs) in many species. This study investigates low-temperature effects
Fan Hu, April L. Clevenger, Peng Zheng, Qiongye Huang, Zhaokai Wang   +4 more
doaj   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Disrupting the Acyl Carrier Protein/SpoT interaction in vivo: identification of ACP residues involved in the interaction and consequence on growth. [PDF]

PLoS ONE, 2012
In bacteria, Acyl Carrier Protein (ACP) is the central cofactor for fatty acid biosynthesis. It carries the acyl chain in elongation and must therefore interact successively with all the enzymes of this pathway.
Sandra Angelini, Laetitia My, Emmanuelle Bouveret   +2 more
doaj   +1 more source

Circadian clock and lipid metabolism disorders: a potential therapeutic strategy for cancer

Frontiers in Endocrinology, 2023
Recent research has emphasized the interaction between the circadian clock and lipid metabolism, particularly in relation to tumors. This review aims to explore how the circadian clock regulates lipid metabolism and its impact on carcinogenesis ...
Mengsi Liu, Mengsi Liu, Mengsi Liu, Mengsi Liu, Zhen Zhang, Yating Chen, Yating Chen, Yating Chen, Yating Chen, Ting Feng, Ting Feng, Ting Feng, Ting Feng, Qing Zhou, Xuefei Tian, Xuefei Tian, Xuefei Tian, Xuefei Tian   +17 more
doaj   +1 more source

Intensified processes for FAME production from waste cooking oil: a technological review [PDF]

, 2013
This article reviews the intensification of fatty acid methyl esters (FAME) production from waste cooking oil (WCO) using innovative process equipment. In particular, it addresses the intensification of WCO feedstock transformation by transesterification,
Aubin, Joelle, Mazubert, Alex, Poux, Martine   +2 more
core   +3 more sources

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Parallel regulation of sterol regulatory element binding protein-2 and the enzymes of cholesterol and fatty acid synthesis but not ceramide synthesis in cultured human keratinocytes and murine epidermis

Journal of Lipid Research, 1998
After permeability barrier perturbation there is an increase in the mRNA levels for key enzymes necessary for lipid synthesis in the epidermis. The mechanism(s) responsible for this regulation is unknown. Sterol regulatory element binding proteins-1a, 1c,
Ian R. Harris, Angela M. Farrell, Walter M. Holleran, Simon Jackson, Carl Grunfeld, Peter M. Elias, Kenneth R. Feingold   +6 more
doaj   +1 more source

Growth of Enterococcus faecalis ∆plsX strains is restored by increased saturated fatty acid synthesis

mSphere, 2023
The Enterococcus faecalis acyl-acyl carrier protein (ACP) phosphate acyltransferase PlsX plays an important role in phospholipid synthesis and exogenous fatty acid incorporation.
Qi Zou, Huijuan Dong, John E. Cronan
doaj   +1 more source