Results 91 to 100 of about 602,888 (282)
Advanced Science, EarlyView.Intermittent fasting reshapes the gut microbiota in diabetic cardiomyopathy, restoring Akkermansia muciniphila and the microbiota‐associated metabolite 1‐methyl‐L‐histidine. This shift is linked to improved cardiac lipid homeostasis, reduced lipid peroxidation, and attenuated myocardial injury, highlighting a gut microbiota–metabolite–lipid axis in ...
Kaiyuan Jiang +7 more
wiley +1 more source
Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery
Advanced Science, EarlyView.Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae +27 more
wiley +1 more source
Fatty Acids and Alcohols [PDF]
, 1969 The fatty acids continue to be one of the most rewarding types of organic compounds studied by geochemists. Almost without exception every research group concerned with fatty acid geochemistry has produced qualitatively new data and relationships.
openaire +1 more source
Efficient and specific analysis of red blood cell glycerophospholipid fatty acid composition. [PDF]
, 2012 Red blood cell (RBC) n-3 fatty acid status is related to various health outcomes. Accepted biological markers for the fatty acid status determination are RBC phospholipids, phosphatidylcholine, and phosphatidyletholamine.
Hans Demmelmair +11 more
core +2 more sources
Advanced Science, EarlyView.A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal +5 more
wiley +1 more source
Microbial engineering to produce fatty alcohols and alkanes. [PDF]
J Ind Microbiol Biotechnol, 2021 Sharma A, Yazdani SS.
europepmc +1 more source
Chemoselective Metabolomics via a Modular Reactivity‐Encoding Platform
Advanced Science, EarlyView.Conventional LC–MS underrepresents numerous metabolites due to heterogeneous ionization efficiencies and matrix interference. Here, we introduce a modular reactivity‐encoding platform (MREP) comprising four alkyne‐tagged probes that selectively derivatize key functional groups, followed by unified click‐chemistry capture to eliminate matrix components ...
Xin Tao +10 more
wiley +1 more source
, 2011 The majority of lipids that interact with a transmembrane protein act as a solvent for the protein, forming a shell around it; these lipids are called annular or boundary lipids.
Bolivar Gonzalez, Juan
core +1 more source
Green Energy & EnvironmentElectrocatalysis offers a promising solution for the oxidative valorization of fatty alcohols, showcasing reaction mildness and sustainability. However, the intrinsically low solubility of fatty alcohols in aqueous electrolytes presents severe mass ...
Ruiqi Du +7 more
doaj +1 more source
Comparison of analytical methods for monitoring autoxidation profiles of authentic lipids
Journal of Lipid Research, 1987 Oxidation profiles of polyunsaturated fatty acids, their esters, and fatty alcohols were compared by several commonly employed analytical procedures. The extent of lipid peroxidation varied with the structure of the specific lipid class.
R S Kim, F S LaBella
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