Results 41 to 50 of about 888,881 (286)

Advances in research on fat infiltration and lumbar intervertebral disc degeneration

Frontiers in Endocrinology, 2022
Low back pain (LBP) is a disabling condition with no available cure, severely affecting patients’ quality of life. Intervertebral disc degeneration (IVDD) is the leading cause of chronic low back pain (CLBP).
Zairan Wang, Zijun Zhao, Shiyuan Han, Xianghui Hu, Liguo Ye, Yongning Li, Yongning Li, Jun Gao   +7 more
doaj   +1 more source

Fatty Pancreas-Centered Metabolic Basis of Pancreatic Adenocarcinoma: From Obesity, Diabetes and Pancreatitis to Oncogenesis

Biomedicines, 2022
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest types of cancer, and it is currently the third most common cause of cancer death in the U.S.A.
Ming-Ling Chang
doaj   +1 more source

High-accuracy detection of supraspinatus fatty infiltration in shoulder MRI using convolutional neural network algorithms

Frontiers in Medicine, 2023
BackgroundThe supraspinatus muscle fatty infiltration (SMFI) is a crucial MRI shoulder finding to determine the patient’s prognosis. Clinicians have used the Goutallier classification to diagnose it.
Juan Pablo Saavedra, Guillermo Droppelmann, Guillermo Droppelmann, Guillermo Droppelmann, Nicolás García, Carlos Jorquera, Felipe Feijoo   +6 more
doaj   +1 more source

Correlation of atrophy and fatty infiltration on strength and integrity of rotator cuff repairs: a study in thirteen patients

, 2007
In 13 patients, the development of supraspinatus muscle atrophy and fatty infiltration after rotator cuff tendon repair was quantified prospectively via magnetic resonance imaging.
Schneeberger, Alberto G, Meyer, Dominik C, Hoppeler, Hans, Gerber, Christian, Schneeberger AG, Gerber C, Meyer DC, Hoppeler, Hans-Heinrich, Hoppeler H   +8 more
core   +1 more source

Bone morphogenetic protein signaling in rotator cuff muscle atrophy and fatty infiltration. [PDF]

, 2015
Backgroundreduced mass (atrophy) and increased fat content (fatty infiltration) of rotator cuff muscles are common complications of large or massive rotator cuff (RC) tears, and are believed to be irreversible even after tendon repairs.
Joshi, Sunil, Ravishankar, Bharat, Kim, Hubert T, Laron, Dominique, Liu, Xuhui, Feeley, Brian T   +5 more
core   +1 more source

The fatty infiltration into cervical paraspinal muscle as a predictor of postoperative outcomes: A controlled study based on hybrid surgery

Frontiers in Endocrinology, 2023
BackgroundThe cervical paraspinal muscle (CPM) has an essential role in positioning, stabilizing and directing the cervical spine. However, information is lacking regarding the influence of CPM on outcomes following anterior cervical surgery.
Junbo He, Tingkui Wu, Chen Ding, Beiyu Wang, Ying Hong, Hao Liu   +5 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Effects of graded doses of sildenafil citrate on liver microanatomy in male albino rats

National Journal of Clinical Anatomy, 2023
Background: Sildenafil citrate (SC) is a vasoerectile drug used to treat impotence caused by erectile dysfunction by inhibiting phosphodiesterase type 5 enzyme.
Sameena Bashir, Ghulam Mohammad Bhat, Shabir Ahmad Khanday, Lateef Ahmad Wani   +3 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source