Results 251 to 260 of about 792,500 (357)

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source

Mechanism of arbutin in metabolic dysfunction-associated fatty liver disease based on multi-omics research. [PDF]

Bioresour Bioprocess
Yin D, Cheng J, Cao H, Wang X, He J, Zhu Y, Li J.   +6 more
europepmc   +1 more source

SULF1/SULF2 reactivation during liver damage and tumour growth [PDF]

, 2016
A Giakoustidis, A Schulze, AP Sahota, C Bret, CL Merry, D Shukla, DC Kroy, G Xu, G Zaman, GK Dhoot, GK Dhoot, Gurtej K. Dhoot, H Barth, H Lemjabbar-Alaoui, J Lai, Joshua I. Murphy, JP Lai, JP Lai, JP Lai, JWY Tuo, K Uchimura, Kurtis Graham, L Hitchins, M Ford-Perriss, M Meyers-Needham, M Morimoto-Tomita, M Tarocchi, MT Joy, P Tátrai, R Gill, R Nawroth, RB Gill, RB Gill, RM Gill, S Ashikari-Hada, S Wang, S Wang, SD Rosen, X Ai, X Ai, Y Xu, YC Kwon   +41 more
core   +1 more source

Glucokinase regulatory protein rs780094 polymorphism is associated with type 2 diabetes mellitus, dyslipidemia, non-alcoholic fatty liver disease, and nephropathy

Ashraf Al Madhoun
openalex   +1 more source

Fatty liver

, 2011
openaire   +1 more source

Restriction of Individual Branched‐Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice

Advanced Science, EarlyView.
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija, Cara L. Green, Michelle M. Sonsalla, Izabelle Marie F. Le, Fan Xiao, Sarah Yandell, Mariah F. Calubag, Michaela E. Trautman, Anna Tobon, Ryan Matoska, Chung‐Yang Yeh, Charles I. Opara, Isaac Grunow, Diana Vertein, Sophia Schlorf, Bailey A. Knopf, Michael J. Rigby, David A. Harris, Mark P. Keller, Alan D. Attie, Luigi Puglielli, Cholsoon Jang, Dudley W. Lamming   +22 more
wiley   +1 more source

Correction: Global assessment of hepatic safety in novel immunotherapies: a systematic review and meta-analysis

Frontiers in Immunology
Minyan Ye, Yinuo Dong, Xiaoyun Li, Xiaoyun Li, Yang Zhi, Yuping Lu, Jieting Tang, Wei Zhong, Xiaohong Lei, Yimin Mao, Sha Huang, Yanyan Song   +11 more
doaj   +1 more source

Association of non-alcoholic fatty liver polygenic risk scores with the incident and progressive non-alcoholic fatty liver disease in Chinese population. [PDF]

Genes Nutr
Zhou Y, Zhou D, Chen S, Yang C, Wu S, Wang X, Lan Y, Lu Y, Zhou M, Wu S, Li M, Wang L.   +11 more
europepmc   +1 more source

Effect of walking exercise on liver enzymes in children with phenylketonuria and non-alcoholic fatty liver disease: A randomized controlled trial

Ali Mohamed Ali Ismail, Mahmoud M. Gohary, Shaimaa Mohamed Mabrouk Bondok, Ahmed Bayuomy Abo Elatta, Nadia Saad Sayed Ahmed El Gressy, Ahmed M. El Melhat, El-Sayed Essam El-Sayed Felaya   +6 more
openalex   +1 more source