Results 221 to 230 of about 1,771,249 (303)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Little to no active faulting likely at Europa's seafloor today. [PDF]

Nat Commun
Byrne PK, Dawson HG, Klimczak C, Regensburger PV, Crane KT, Catalano JG, Elder CM, Foley BJ, German CR, Green AP, Hemingway DJ, Melwani Daswani M, Panning MP, Randolph-Flagg N, Sherwood Lollar B, Skemer P, Vance SD, Wiens DA.   +17 more
europepmc   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Real-Time Zero-Sequence-Voltage Estimation and Fault-Tolerant Control for an Open-Winding Five-Phase Fault-Tolerant Fractional-Slot Concentrated-Winding IPM Motor Under Inter-Turn Short-Circuit Fault. [PDF]

Sensors (Basel)
Cui R, Ji Q, Zhang S, Li H.
europepmc   +1 more source

Distribution Network Sag Assessment under Stochastic Faults Based on Network Transformation and Fitting Integral

, 2020
Hongxin Li, Huaying Zhang, Jingwen Ai, Yan Li   +3 more
openalex   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Off-fault damage controls near-surface rupture behaviour in soft sediments. [PDF]

Nat Commun
De Paola N, Bullock RJ, Holdsworth RE, Marco S, Nielsen S.   +4 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Concurrent Incipient Fault Diagnosis in Three-Phase Induction Motors Using Discriminative Band Energy Analysis of AM-Demodulated Vibration Envelopes. [PDF]

Sensors (Basel)
de Godoy MB, Lucas GB, Andreoli AL.
europepmc   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source