Results 171 to 180 of about 43,176 (313)

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Tsunamigenic fault structures revealed in the 2024 Noto earthquake (M7.6) rupture area. [PDF]

open access: yesSci Rep
Park JO   +8 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

The May 29 2008 earthquake aftershock sequence within the South Iceland Seismic Zone: Fault locations and source parameters of aftershocks

open access: yes
The mid-Atlantic plate boundary breaks up into a series of segments across Iceland. The South Iceland Seismic Zone (SISZ) is a complex transform zone where left-lateral E-W shear between the Reykjanes Peninsula Rift Zone and the Eastern Volcanic Zone is ...
Guðmundsson, O.   +5 more
core  

Imaging slow failure in triaxially deformed Etna basalt using 3D acoustic-emission location and X-ray computed tomography

open access: yes, 2007
We have deformed basalt from Mount Etna (Italy) in triaxial compression tests under an effective confining pressure representative of conditions under a volcanic edifice (40 MPa), and at a constant strain rate of 5 similar to 10(-6) s(-1).
Thompson, BD   +4 more
core  

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