Results 91 to 100 of about 7,855,293 (193)
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Current on secondary winding the inductive superconductor fault current limiter [PDF]
, 2010 W niniejszym artykule przedstawiono zagadnienie związane z badaniem przebiegu prądu w zwartym uzwojeniu wtórnym nadprzewodnikowego ogranicznika prądu typu indukcyjnego w chwili wystąpienia zwarcia w obwodzie, w którym znajduje się ogranicznik.This paper ...
Kafarski, M.
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Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Fault-current limiter using a superconducting coil [PDF]
, 1982 A novel circuit, consisting of solid-state diodes and a biased superconducting coil, for limiting the fault currents in three-phase ac systems is presented.
Paice, D. A., Boenig, H. J.
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USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Presaturated iron‐core fault current limiters for MVDC power system applications
IET Electric Power ApplicationsThis paper presents design and dynamic performance investigation of a 25kV full‐scale, modular topology (arranged on the sides of a regular hexagon), medium voltage direct current (MVDC) permanent magnet (PM) biased presaturated fault current limiter ...
Ibrahim A. Metwally, Mohamed Eladawy
doaj +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Wind Power Plant Enhancement with a Fault-Current Limiter: Preprint [PDF]
, 2011 This paper investigates the capability of a saturable core fault-current limiter to limit the short circuit current of different types of wind turbine ...
Muljadi, E., Gevorgian, V., DeLaRosa, F.
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