Results 91 to 100 of about 6,082 (303)

Effects of high pressure on the physical properties of MgB2

, 2010
The synthesis of MgB2-based materials under high pressure gave the possibility to suppress the evaporation of magnesium and to obtain near theoretically dense nanograined structures with high superconducting, thermal conducting, and mechanical ...
Danilenko, N., Dellith, J., Dub, S., Eisterer, M., Fesenko, I., Gawalek, W., Goldacker, W., Habisreuther, T., Karau, F., Kozyrev, A., Litzkendorf, D., Meerovich, V., Moshchil, V., Nagorny, P., Noudem, J., Prikhna, T., Rindfleisch, M., Savchuk, Ya., Schmidt, Ch., Serga, M., Sergienko, N., Sokolovsky, V., Soldatov, A., Sverdun, V., Tkach, V., Tompsic, M., Turkevich, V., Weber, H. W., Wendt, M., You, S.   +29 more
core   +1 more source

Fault management strategies and architecture design for turboelectric distributed propulsion [PDF]

, 2016
The TeDP concept has been presented as a possible solution to reduce aircraft emissions despite the continuing trend for increased air traffic. However, much of the benefit of this concept hinges on the reliable transfer of electrical power from the ...
Flynn, M.-C., Galloway, S.J., Jones, C.E., Norman, P.J.   +3 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Distributed voltage control in electrical power systems [PDF]

, 2009
Voltage instability stems from the attempt of load dynamics to restore power consumption beyond the capability of the combined transmission and generation system.
Boel, René, Moradzadeh, Mohammad
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Study on Recovery Time of Conduction-Cooled Resistive Superconducting Fault Current Limiter

Energies
This paper presents the influence of superconducting tape insulation on the recovery time of superconducting fault current limiters. The analysis is based on the experimental results of short-circuit tests.
Janusz Kozak
doaj   +1 more source

A novel time domain protection technique for multi-terminal HVDC networks utilising travelling wave energy [PDF]

, 2018
Fault vulnerability and protection issues are major challenge in realising multi-terminal HVDC transmission system, also termed HVDC grids. This paper presents a novel time domain and transient based protection technique for application to HVDC grids ...
Adamczyk, Andrzej, Griffiths, Alison, Ha, Hengxu, Ikhide, Monday, Subramanian, Sankara, Tennakoon, Sarath   +5 more
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Fault Ride-through Capability Enhancement of Voltage Source Converter-High Voltage Direct Current Systems with Bridge Type Fault Current Limiters

Energies, 2017
This paper proposes the use of bridge type fault current limiters (BFCLs) as a potential solution to reduce the impact of fault disturbance on voltage source converter-based high voltage DC (VSC-HVDC) systems.
Md Shafiul Alam, Mohammad Ali Yousef Abido   +1 more
doaj   +1 more source