Results 101 to 110 of about 1,306 (255)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Fault Current Limiters for LVRT Enhancement in Wind Turbine Systems: Technologies, Trade-Offs, and Comparative Simulation Insights

Energies
This paper presents a comprehensive review and comparative evaluation of Fault Current Limiter (FCL) technologies for enhancing the Low-Voltage Ride-Through (LVRT) capability of Wind Turbine Generation Systems (WTGSs).
Mehdi Firouzi, Mirhamed Pourmirasghariyan, Kumars Rouzbehi, Manuel R. Arahal   +3 more
doaj   +1 more source

Integration of fault current limiters in power distribution networks

, 2004
The continuous growth of electrical energy demand is resulting in a corresponding increase in the short-circuit current in power networks. Several solutions have been implemented, including the use of Fault current limiters, in order to reduce circuit ...
Ahmed, Mohamed Mostafa Ramadan, Chu, K.R., Putrus, Ghanim, Ran, Li, Funabashi, Toshihisa   +4 more
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

An integral backstepping controller design for compensated distribution networks with rapid earth fault current limiters in bushfire prone areas

, 2022
An integral backstepping controller design for compensated distribution networks with rapid earth fault current limiters in bushfire prone ...
MA Mahmud (9864944), NK Roy (14118249), TK Roy (13935330)   +2 more
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

A hybrid sliding mode control scheme for rapid earth fault current limiters in compensated distribution networks in bushfire prone areas

, 2023
A hybrid sliding mode control scheme for rapid earth fault current limiters in compensated distribution networks in bushfire prone ...
MdAbdul Barik (15894908), Tushar Kanti Roy (13493221), ABM Nasiruzzaman (15767207), A Mahmud (5837783)   +3 more
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Presaturated iron‐core fault current limiters for MVDC power system applications

IET Electric Power Applications
This paper presents design and dynamic performance investigation of a 25kV full‐scale, modular topology (arranged on the sides of a regular hexagon), medium voltage direct current (MVDC) permanent magnet (PM) biased presaturated fault current limiter ...
Ibrahim A. Metwally, Mohamed Eladawy
doaj   +1 more source

A central microgrid protection system for networks with fault current limiters

, 2011
Large deployments of Distributed Generators (DGs) have substantial impacts on the structure of existing networks. In order to tackle these issues, it has been proposed to divide the network into smaller manageable sets which can be more effectively and ...
Zayegh, Aladin, Taha Selim Ustun, Ozansoy, Cagil, Cagil Ozansoy, Ustun, Taha Selim, Aladin Zayegh   +5 more
core   +1 more source