Results 101 to 110 of about 6,082 (303)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Research on Coordination and Optimal Configuration of Current Limiting Devices in HVDC Grids

IEEE Access, 2019
This paper proposes a collaborative optimal configuration method of current limiting reactors (CLRs) and fault current limiters (FCLs) in the modular multilevel converter (MMC)-based high voltage direct current (HVDC) grids. The calculation methods of dc
Jun Mei, Guangyao Fan, Rui Ge, Bingbing Wang, Pengfei Zhu, Lingxiao Yan   +5 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Fault Current Limiters for LVRT Enhancement in Wind Turbine Systems: Technologies, Trade-Offs, and Comparative Simulation Insights

Energies
This paper presents a comprehensive review and comparative evaluation of Fault Current Limiter (FCL) technologies for enhancing the Low-Voltage Ride-Through (LVRT) capability of Wind Turbine Generation Systems (WTGSs).
Mehdi Firouzi, Mirhamed Pourmirasghariyan, Kumars Rouzbehi, Manuel R. Arahal   +3 more
doaj   +1 more source

Understanding the impact of failure modes of cables for the design of turbo-electric distributed propulsion electrical power systems. [PDF]

, 2016
The turbo-electric distributed propulsion (TeDP) concept has been proposed to enable future aircraft to meet ambitious, environmental targets as demand for air travel increases.
Galloway, S.J., Jones, C.E., Nolan, S., Norman, P.J.   +3 more
core  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Enhancement of DUBAL Network Operational Performance Using Resistive High Temperature Superconducting Fault Current Limiter

Energies, 2019
Power systems under expansion suffer from escalating fault levels that impact equipment integrity, operational flexibility, and the overall security of the system.
Hamood Naji, Noureddine Harid, Huw Griffiths   +2 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source