Results 71 to 80 of about 3,067 (278)

High Integrity Localization of Intelligent Vehicles with Student’s t Filtering and Fault Exclusion

, 2023
International audienceHigh-integrity localization is a key element for safety-critical applications like autonomous driving. The navigation filter plays a crucial role in merging sensor data to estimate an accurate pose and calculate a confidence ...
Bonnifait, Philippe, Salvatico, Nicolò, Al Hage, Joelle   +2 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Filter-Type Fault Detection and Exclusion on Multi-Frequency GNSS Receiver

, 2007
本論文之議題為探討衛星故障之偵測與排除 (fault detection and exclusion; FDE)，其目地是為了偵測因衛星故障所引發之嚴重定位誤差，並且進一步將產生誤差的來源消除，以使導航能夠延續；在此提出分別以多頻 (multi-frequency) 技術、自我迴歸移動平均 (autoregressive moving average; ARMA) 濾波器、卡爾曼濾波器 (Kalman filter) 為基礎之三種演算法，以改進現有之故障偵測與排除演算法 ...
Tsai, Yi-Hsueh, 蔡宜學
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Dual-Frequency Multi-Constellation Global Navigation Satellite System/Inertial Measurements Unit Tight Hybridization for Urban Air Mobility Applications

Aerospace
A global navigation satellite system (GNSS) for remotely piloted aircraft systems (RPASs) positioning is essential, thanks to the worldwide availability and continuity of this technology in the provision of positioning services.
Gianluca Corraro, Federico Corraro, Andrea Flora, Giovanni Cuciniello, Luca Garbarino, Roberto Senatore   +5 more
doaj   +1 more source

AI Solutions for MDS: Artificial Intelligence Techniques for Misuse Detection and Localisation in Telecommunication Environments

, 2006
This report considers the application of Articial Intelligence (AI) techniques to the problem of misuse detection and misuse localisation within telecommunications environments.
Mintram, Robert, Phalp, Keith T., Vincent, Jonathan, Bauerdick, H., Gottfried, B., Muthuraman, S., Anyakoha, Chukwudi   +6 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Integrity Monitoring for BDS/INS Real-Time Kinematic Positioning Between Two Moving Platforms

Remote Sensing
In recent years, the rapid development of moving platforms, especially unmanned aerial vehicles (UAVs) and unmanned ground vehicles (UGVs), has promoted their widespread applications in various fields such as precision agriculture and formation flight ...
Yangyang Li, Weiming Tang, Chenlong Deng, Xuan Zou, Siyu Zhang, Zhiyuan Li, Yipeng Wang   +6 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

GPS Satellite Fault Detection and Exclusion Using Bank of Kalman Filters

, 2007
In this thesis, a new approach based on the bank of Kalman filters is proposed to reduce the fault detection time and the incorrect exclusion rate. The dynamic behavior of the failure vector can be described as P-V (position-velocity) model。By applying ...
Lee, Chia-Cheng, 李嘉政
core