Results 101 to 110 of about 101,205 (396)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Global Fault-Tolerant Control of Underactuated Aerial Vehicles with Redundant Actuators

International Journal of Aerospace Engineering, 2019
In this paper, we consider the fault-tolerant control problem for aerial vehicles with redundant actuators. The redundant actuator brings difficulty in fault identification and isolation.
Yushu Yu, Yiqun Dong
doaj   +1 more source

Design of distributed Fault Detection and Isolation systems

IFAC-PapersOnLine, 2015
Safety operating of controlled systems requires the validation of the data produced by the sensors. The objective of this validation is to detect erroneous data and then not to transmit these data to the control or other algorithms. One possibility to detect and isolate faulty data rests on the online evaluation of Analytical Redundancy Relations (ARRs)
Gehin, Anne-Lise, Ould Bouamama, Belkacem   +1 more
openaire   +1 more source

Plug-and-Play Fault Detection and Isolation for Large-Scale Nonlinear Systems With Stochastic Uncertainties

IEEE Transactions on Automatic Control, 2019
This paper proposes a novel scalable model-based fault detection and isolation approach for the monitoring of nonlinear large-scale systems, consisting of a network of interconnected subsystems.
F. Boem, S. Riverso, G. Ferrari-Trecate, T. Parisini   +3 more
semanticscholar   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Advanced fault detection methodologies and communication protocols for DC micro grid -A technical review

Results in Engineering
DC microgrids are increasingly adaptable to contemporary electrical systems due to their superior capacity to integrate distributed energy resources (DER) and enhance the overall stability of the grid.
Athira Earath Shivadasan, Prabhakar Karthikeyan Shanmugam   +1 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

A Sparse Autoencoder-Based Unsupervised Scheme for Pump Fault Detection and Isolation [PDF]

, 2020
Xiaoxia Liang, Fang Duan, Ian Bennett, David Mba   +3 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Communications and tracking expert systems study [PDF]

The original objectives of the study consisted of five broad areas of investigation: criteria and issues for explanation of communication and tracking system anomaly detection, isolation, and recovery; data storage simplification issues for fault ...
Feagin, Terry, Leibfried, T. F., Overland, David   +2 more
core   +1 more source