Results 51 to 60 of about 7,503 (310)
Adaptive Fault Isolation and System Reconfiguration Method for GNSS/INS Integration
Appropriate fault isolation and system reconfiguration scheme is of great significance to ensure the reliability and precision of the tightly coupled global navigation satellite system/inertial navigation system (GNSS/INS).
Chuang Zhang +4 more
doaj +1 more source
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
A Bayesian Approach to Fault Identification in the Presence of Multi-component Degradation
Fault diagnosis typically consists of fault detection, isolation and identification. Fault detection and isolation determine the presence of a fault in a system and the location of the fault.
Yufei Lin, Skaf Zakwan, Ian Jennions
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Model based fault detection and diagnosis using structured residual approach in a multi-input multi-output system [PDF]
Fault detection and isolation (FDI) is a task to deduce from observed variable of the system if any component is faulty, to locate the faulty components and also to estimate the fault magnitude present in the system.
Asokan A., Sivakumar D.
doaj +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Fault Detection and Isolation in Critical Infrastructure Systems [PDF]
Critical infrastructure systems (CIS) are complex large-scale systems which in turn require highly sophisticated supervisory control systems to ensure that high performance can be achieved and maintained under adverse conditions. The global CIS Real-Time Control (RTC) need of operating in adverse conditions involves, with a high probability, sensor and
Puig Cayuela, Vicenç +3 more
openaire +2 more sources
Optimal Sensor Placement in Lithium-Ion Battery Pack for Fault Detection and Isolation [PDF]
Ye Cheng +2 more
openalex +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source

