Results 51 to 60 of about 2,947,084 (288)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Paleoearthquakes of the Düzce fault (North Anatolian Fault Zone): Insights for large surface faulting earthquake recurrence [PDF]

, 2008
Copyright 2008 by the American Geophysical Union.The 12 November 1999 Mw 7.1 earthquake ruptured the Düzce segment of the North Anatolian Fault Zone and produced a ∼40-km-long surface rupture.
D. Pantosti, Palyvos, N, S. Pucci, C. Zabci, D'Addezio, G, N. Palyvos, Zabci, C, De Martini, PM, Zabci, C., Pucci, S, G. D'Addezio, Pucci, S., D'Addezio, G., Pantosti, D., P. E. F. Collins, Palyvos, N., P. M. De Martini, De Martini, P. M., Pantosti, D, Collins, PEF, Collins, P. E. F.   +20 more
core   +1 more source

Fault recognition method of smart grid data acquisition system based on FNN and sequential DS fusion

Cognitive Computation and Systems, 2021
It is of significant practical importance to ensure the operational safety of the smart grid, which requires real‐time fault diagnosis and identifying what causes it based on an enormous amount of data.
Hanzhe Qiao, Quanbo Ge, Haoyu Jiang, Ziyi Li, Zilong You, Jianmin Zhang, Fengjuan Bi, Chunlei Yu   +7 more
doaj   +1 more source

Identification of methods with low fault risk [PDF]

Proceedings of the 40th International Conference on Software Engineering: Companion Proceeedings, 2018
Test resources are usually limited and therefore it is often not possible to completely test an application before a release. Therefore, testers need to focus their activities on the relevant code regions. In this paper, we introduce an inverse defect prediction approach to identify methods that contain hardly any faults. We applied our approach to six
Rainer Niedermayr, Tobias Röhm, Stefan Wagner 0001   +2 more
openaire   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Fault Diagnosis Algorithm Based on Adjustable Nonlinear PI State Observer and Its Application in UAV Fault Diagnosis

Algorithms, 2021
Aiming at the problem of fault diagnosis in continuous time systems, a kind of fault diagnosis algorithm based on adaptive nonlinear proportional integral (PI) observer, which can realize the effective fault identification, is studied in this paper ...
Qing Miao, Juhui Wei, Jiongqi Wang, Yuyun Chen   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Least order fault and model detection using multi-models [PDF]

, 2009
Multi-model based fault detection is often a viable alternative to various multi-model based state estimation techniques using banks of Kalman filters.
A. Varga, Varga, Andreas
core   +1 more source