Results 71 to 80 of about 39,327 (311)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Research on a Method for Identifying Key Fault Information in Substations

Computation
The identification of critical fault information plays a crucial role in ensuring the reliability and stability of power systems. However, existing fault-identification technologies heavily rely on high-dimensional sensor data, which often contain ...
Pan Zhang, Lei Guo, Zhicheng Huang, Zhoupeng Rao, Ying Zhang, Zhi Sun, Rui Xu, Deng Li   +7 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Fault Detection of Gearbox from Inverter Signals Using Advanced Signal Processing Techniques

, 2012
The gear faults are time-localized transient events so time-frequency analysis techniques (such as the Short-Time Fourier Transform, Wavelet Transform, motor current signature analysis) are widely used to deal with non-stationary and nonlinear signals ...
Gu, Fengshou, Pislaru, Crinela, Ball, Andrew, Lane, Mark, Ball, A. D., Gu, F., Pislaru, C., Lane, M.   +7 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Fault severity diagnosis of rolling element bearings based on kurtogram and envelope analysis

, 2014
Faults in rolling element bearing are among the main causes of breakdown in rotating machines. Vibration is an effective technique for machine condition monitoring.
Gu, Fengshou, Chen, Zhi, Rehab, Ibrahim, Ball, Andrew, Rehab, Ibrahim.A.M, Wang, Tie, Tian, Xiange   +6 more
core  

A Fault-Severity-Assessment Model Based on Spatiotemporal Feature Fusion and Scene Generation for Optical Current Transformer

Energies
Accurately identifying the fault type of an optical current transformer (optical CT) and evaluating the fault severity can provide strong support for the operation and maintenance of a direct current (DC) power system.
Haiwang Jin, Haiqing An, Zhendong Li, Zihao Tong, Haonan Dai, Fei Wang, Mengke Xie   +6 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Application of Phase Space Warping on Damage Tracking for Bearing Fault

, 2012
Nowadays, the significance of keeping equipment function properly each time is obvious. If equipment fails during its use, it may have disastrous consequences.
Gu, Fengshou, Hu, Niaoqing, Hu, Lei, Fan, Bin   +3 more
core   +1 more source