Results 81 to 90 of about 2,947,084 (288)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Research on Diesel Engine Fault Status Identification Method Based on Synchro Squeezing S-Transform and Vision Transformer

, 2023
The reliability and safety of diesel engines gradually decrease with the increase in running time, leading to frequent failures. To address the problem that it is difficult for the traditional fault status identification methods to identify diesel engine
Yunbin Yan, Enzhi Dong, Zhonghua Cheng, Zichang Liu, Siyu Li, Rongcai Wang   +5 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Bispectrum of stator phase current for fault detection of induction motor [PDF]

, 2009
A number of research studies has shown that faults in a stator or rotor generally show sideband frequencies around the mains frequency (50 Hz) and at higher harmonics in the spectrum of the Motor Current Signature Analysis (MCSA).
Gu, Fengshou, Ball, Andrew, Gu, Fengshu, Sinha, Jyoti K.; id_orcid, Treetrong, Juggrapong, Sinha, Jyoti K.   +5 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Design of Fault Detection, Identification and Recovery Algorithms for a 3-Axis Stabilized Satellite [PDF]

فصلنامه علوم و فناوری فضایی, 2012
A Fault Tolerant attitude control system has been designed in this paper, which provides abilities of fault detection, identification and recovery. For this purpose, nonlinear dynamics of satellite is modeled based on Takagi-Sugeno method, which enables ...
H. Bolandi, M. Haghparast, M. Abedi
doaj  

Bayesian Diagnosability and Active Fault Identification

2025 IEEE 64th Conference on Decision and Control (CDC)
We study fault identification in discrete-time nonlinear systems subject to additive Gaussian white noise. We introduce a Bayesian framework that explicitly accounts for unmodeled faults under reasonable assumptions. Our approach hinges on a new quantitative diagnosability definition, revealing when passive fault identification (FID) is fundamentally ...
Chun-Wei Kong, Jay W. McMahon, Morteza Lahijanian   +2 more
openaire   +4 more sources

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

IDENTIFICATION OF MULTIPLE FAULTS IN ROTOR SYSTEMS

Journal of Sound and Vibration, 2002
Many papers are available in the literature about identification of faults in rotor systems. However, they generally deal only with a single fault, usually an unbalance. Instead, in real machines, the case of multiple faults is quite common: the simultaneous presence of a bow (due to several different causes) and an unbalance or a coupling misalignment
BACHSCHMID, NICOLO', PENNACCHI, PAOLO EMILIO LINO MARIA, VANIA, ANDREA TOMMASO   +2 more
openaire   +1 more source