Results 91 to 100 of about 1,108,433 (294)

The importance of selecting the optimal number of principal components for fault detection using principal component analysis [PDF]

, 2012
Includes summary.Includes bibliographical references.Fault detection and isolation are the two fundamental building blocks of process monitoring. Accurate and efficient process monitoring increases plant availability and utilization.
Khwambala, Patricia Helen
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

A Safe Reinforcement Learning Approach for Active Fault Diagnosis

, 2023
reservedFault Detection e Fault Isolation hanno un ruolo di primo piano nei sistemi automatizzati. In questo ambito, delle tecniche emergenti, note come Active Fault Diagnosis, stanno acquistando popolarità.
ZACCARIA, VALENTINA
core  

Synergistic frameworks for sensor fault isolation and accommodation in grid-side converters

Journal of Automation and Intelligence
The stable and reliable operation of grid-integrated renewable energy systems requires advanced control and coordination of grid-side converters (GSCs), utilizing the feedback measurements of voltage and current sensors from both the direct current (DC ...
Faizan Mehmood, Lenos Hadjidemetriou, Panayiotis M. Papadopoulos, Marios M. Polycarpou   +3 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Time-Varying Fault Diagnosis for Asynchronous Multisensor Systems Based on Augmented IMM and Strong Tracking Filtering

Journal of Control Science and Engineering, 2018
A fault detection, isolation, and estimation approach is proposed in this paper based on Interactive Multimodel (IMM) fusion filtering and Strong Tracking Filtering (STF) for asynchronous multisensors dynamic systems. Time-varying fault is considered and
Yanyan Hu, Xiaoling Xue, Zengwang Jin, Kaixiang Peng   +3 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Application of a Fault Detection and Isolation System on a Rotary Machine

International Journal of Rotating Machinery, 2013
The paper illustrates the design and the implementation of a Fault Detection and Isolation (FDI) system to a rotary machine like a multishaft centrifugal compressor.
Silvia M. Zanoli, Giacomo Astolfi
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Numerically reliable methods for optimal design of fault detection filters [PDF]

, 2005
The design problem of fault detection and isolation filters is formulated as a model matching problem and solved using an H2-or H1-norm optimization approach.
Varga, Andreas
core