Results 41 to 50 of about 12,788 (262)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

HYBRID DEEP FAULT DETECTION AND ISOLATION: COMBINING DEEP NEURAL NETWORKS AND SYSTEM PERFORMANCE MODELS

International Journal of Prognostics and Health Management, 2019
With the increased availability of condition monitoring data on the one hand and the increased complexity of explicit system physics-based models on the other hand, the application of data-driven approaches for fault detection and isolation has recently ...
Manuel Arias Chao, Chetan Kulkarni, Kai Goebel, Olga Fink   +3 more
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

A Bayesian Approach to Fault Identification in the Presence of Multi-component Degradation

International Journal of Prognostics and Health Management, 2017
Fault diagnosis typically consists of fault detection, isolation and identification. Fault detection and isolation determine the presence of a fault in a system and the location of the fault.
Yufei Lin, Skaf Zakwan, Ian Jennions
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

A New Fault Simulation Test and Evaluation Method of Distribution Automation System

MATEC Web of Conferences, 2016
This paper proposes a fault simulation test method suitable for five divisions of power supply area. Distribution network structures are classified according to different power supply areas and more active interference is injected into test cases, which ...
Fan Wenbo, An Yu, Liu Dong, Guan Shilei
doaj   +2 more sources

Solid-State Circuit Breaker Topology Design Methodology for Smart DC Distribution Grids with Millisecond-Level Self-Healing Capability

Energies
To address the challenges of prolonged current isolation times and high dependency on varistors in traditional flexible short-circuit fault isolation schemes for DC systems, this paper proposes a rapid fault isolation circuit design based on an adaptive ...
Baoquan Wei, Haoxiang Xiao, Hong Liu, Dongyu Li, Fangming Deng, Benren Pan, Zewen Li   +6 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

SENSOR FAULTS DIAGNOSIS IN AIRCRAFT LATERAL FLIGHT CONTROL USING MODEL BASED APPROACHES

Havacılık ve Uzay Teknolojileri Dergisi, 2015
In this paper, sensor fault detection and isolation schemes are proposed. Fault detection and isolation techniques are used in fail safe control systems such as aerospace. In these systems, failures can cause to arise undesirable results.
Emre Kıyak
doaj