Results 131 to 140 of about 538,374 (350)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Winding-to-ground fault location in power transformer windings using combination of discrete wavelet transform and back-propagation neural network. [PDF]
Chiradeja P, Ngaopitakkul A.
europepmc +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Machine Learning-Based Fault Location for Smart Distribution Networks Equipped with Micro-PMU. [PDF]
Mirshekali H +3 more
europepmc +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Fault location method for multi-section hybrid lines considers velocity uncertainty
Fault location accuracy of traveling wave method is constrained to the reliable traveling wave velocity. In this paper, a novel fault traveling waves location method is proposed to eliminate the effects of velocity uncertainty on hybrid lines’ fault ...
Liwei Xie +5 more
doaj +1 more source
Random Forest Regressor-Based Approach for Detecting Fault Location and Duration in Power Systems. [PDF]
El Mrabet Z +3 more
europepmc +1 more source
Fault location of hybrid distribution lines based on empirical mode decomposition
Yundong Song +3 more
openalex +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source

