Results 181 to 190 of about 1,502 (257)

CLRe: A Synergistic Dual‐Engine Framework for One‐Step Retrosynthesis Prediction

Advanced Science, EarlyView.
CLRe uses a contrastive difficulty score to order pretrained seq2seq fine‐tuning for retrosynthesis. Reaction embeddings define the ranking score, and a cumulative easy‐to‐hard schedule expands from the easiest subset to the full training set while earlier examples remain active.
Tianhao Su, Xitao Wang, Musen Li, Guanhua Qin, Shunbo Hu, Tong‐Yi Zhang   +5 more
wiley   +1 more source

Markov chain-based turnout state prediction and lifespan simulation. [PDF]

Sci Rep
Wu Z, He W, Wu Z, Gu S, Li C, Guo J.
europepmc   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

Infrared Imaging for Autonomous Power Inspection: A Review from Detector to System Integration. [PDF]

Sensors (Basel)
Guo Y, Du Y, Mao R, Zhao Y, Guo J.
europepmc   +1 more source

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

Advanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li, Haojie Fu, Zhe Wang, Xuanzhou Chen, Ruhong Zhang, Xudong Wang, Louis D. Zhang, Xiang Li, Datao Li   +8 more
wiley   +1 more source

Timing of Return to Driving After Volar Locking-Plate Fixation of Distal Radius Fractures Without Wrist Immobilization: A Prospective Driving Simulator Study. [PDF]

JB JS Open Access
Shirato R, Yamanaka Y, Goshima W, Oda T, Wada T.   +4 more
europepmc   +1 more source

Bistable Networks Enable Complex Shape Changes

Advanced Science, EarlyView.
Transition‐controlled metamaterials are networks of bistable mechanical memory that store local binary states and express them as global shape change. By decoupling low‐force programming from high‐force holding, a single lattice is reconfigured into distinct 2D profiles and 3D surfaces without continuous actuation, enabling reusable morphing materials ...
Sawyer Thomas, Jeffrey Lipton
wiley   +1 more source

Analyzing Fault Reactivation Behavior Using InSAR, Stress Inversion, and Field Observations During the 2025 Sındırgı Earthquake Sequence, Simav Fault Zone, Western Türkiye. [PDF]

Sensors (Basel)
Kutoğlu ŞH, Softa M, Akgün E, Nas M, Topal S.   +4 more
europepmc   +1 more source

Sheet‐Size‐Dependent Mosaicity of 2D Phyllosilicate Membranes

Advanced Science, EarlyView.
This study explores how the size of 2D vermiculite sheets affects the structure of laminar membranes. High‐resolution x‐ray diffraction reveals how sheet size governs structural disorder and crystallinity. These changes directly impact ion permeability.
Min A Kim, Paul A. Fenter, Sang Soo Lee, Katrina I. Sparks, Yining Liu, Jeffrey W. Elam, Seth B. Darling   +6 more
wiley   +1 more source

Maximum size and magnitude of injection-induced slow slip events. [PDF]

Sci Adv
Sáez A, Passelègue F, Lecampion B.
europepmc   +1 more source