Results 51 to 60 of about 18,266 (267)

DIAGNOSIS WITH A FUNCTION-FAULT MODEL

Applied Artificial Intelligence, 1989
This paper introduces a domain model for use in diagnostic problem solving. It emphasizes functional decomposition, rather than behavior, cause-effect, or spatial structure, and represents explicitly the faults of a system together with its possible explanations.
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

The Random Fault Model

sponsorship: A special thanks to Vincent Rijmen for the helpful discussions. This work was supported by CyberSecurity Research Flanders with reference number VR20192203. (CyberSecurity Research Flanders|VR20192203)
Dhooghe, Siemen, Nikova, Svetla
openaire   +2 more sources

Advanced Fault Tree Modeling

J. Univers. Comput. Sci., 1999
JUCS - Journal of Universal Computer Science Volume Nr.
openaire   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Development and Implementation of Physics-Informed Neural ODE for Dynamics Modeling of a Fixed-Wing Aircraft Under Icing/Fault

Guidance, Navigation and Control
Accurate dynamics modeling is crucial for the safety and control of fixed-wing aircraft under perturbation (e.g. icing/fault). In this work, we propose a physics-informed Neural Ordinary Differential Equation (PI-NODE)-based scheme for aircraft dynamics ...
Jinyi Ma, Yiyang Li, Jingqi Tu, Yiming Zhang, Jianliang Ai, Yiqun Dong   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Short-Circuit Calculation and Overcurrent Relay Protection in AC Microgrids: A Review

Energies
AC microgrids with high penetration of inverter-based distributed energy resources (IBDERs) introduce major protection challenges due to reduced fault current levels, bidirectional power flows, and control-dependent fault behavior. Under these conditions,
Aleksej Zilovic, Luka Strezoski, Chad Abbey   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source