Results 51 to 60 of about 23,612 (232)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

A prediction model and zonal evaluation method for concealed fault density based on VMD-SABO-XGBoost

Meikuang Anquan
Concealed fault is an important geological problem in coal mine production. The scale of concealed fault is often small and it is difficult to predict accurately.
Mingguo HUA, Aitao ZHOU, Shuai MA, Yida WANG, Yanxu LI, Kang LI, Mengyao LI   +6 more
doaj   +1 more source

Regional Landslide Potential Mapping in Earthquake-Prone Areas of Kepahiang Regency, Bengkulu Province, Indonesia

Geosciences, 2018
Kepahiang regency is an area above the Musi segment of the Sumatran fault system. This condition makes the study area prone to natural disasters such as landslides in the slope area caused by earthquakes due to tectonic plate movement.
Arif Ismul Hadi, Kirbani Sri Brotopuspito, Subagyo Pramumijoyo, Hary Christady Hardiyatmo   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

A Physics-Based Seismic Risk Assessment of the Qujiang Fault: From Dynamic Rupture to Disaster Estimation

International Journal of Disaster Risk Science
This study achieved the construction of earthquake disaster scenarios based on physics-based methods—from fault dynamic rupture to seismic wave propagation—and then population and economic loss estimations.
Yilong Li, Zijia Wang, Zhenguo Zhang, Yuhao Gu, Houyun Yu   +4 more
doaj   +1 more source

Influencing factors of suicide in hospitalized patients with mental disorders: a retrospective study using medical malpractice cases in China

Frontiers in Psychiatry
ObjectiveThis study aims to reveal the suicide risk factors in specific situations of medical malpractice.MethodsWe conducted a systematic analysis using the medical malpractice case data from the judgment search system on China Judgments Online ...
Qiang Wang, Daming Sun, Guangjian Li, Lin Li, Hongyan Li, Yajun Xu   +5 more
doaj   +1 more source