Results 61 to 70 of about 18,534 (262)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Distributed Multi-Level Supervision to Effectively Monitor the Operations of a Fleet of Autonomous Vehicles in Agricultural Tasks

Sensors, 2015
This paper describes a supervisor system for monitoring the operation of automated agricultural vehicles. The system analyses all of the information provided by the sensors and subsystems on the vehicles in real time and notifies the user when a failure ...
Jesús Conesa-Muñoz, Mariano Gonzalez-de-Soto, Pablo Gonzalez-de-Santos, Angela Ribeiro   +3 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Robust fault recovery strategy for multi-source flexibly interconnected distribution networks in extreme disaster scenarios

Frontiers in Energy Research
To enhance the resilience of power distribution networks against extreme natural disasters, this article introduces a robust fault recovery strategy for multi-source, flexible interconnected power distribution networks, particularly under scenarios of ...
Tang Baofeng, He Lei, Zhou Lidong, Zhao Hongtao, Wang Kang, Zhang Pengliang   +5 more
doaj   +1 more source

Quantifying fault recovery in multiprocessor systems

Mathematical and Computer Modelling, 1993
We formalize and quantify various aspects of reliable computing with emphasis on efficient fault recovery. The mathematical model which proves to be most appropriate is provided by the theory of graphs. We have developed new measures for fault recovery and observe that the value of elements of the fault recovery vector depend not only on the ...
Harary, Frank, Malek, Miroslaw
openaire   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

A Graph Deep Reinforcement Learning-Based Fault Restoration Method for Active Distribution Networks

Energies
The topology of distribution networks changes frequently, and the uncertainty of load level and distributed generator (DG) output makes the operation scenarios more complex and variable.
Yangqing Dan, Hui Zhong, Chenxuan Wang, Jun Wang, Yanan Fei, Le Yu   +5 more
doaj   +1 more source

MPLS-based Network Fault Recovery Research

International Journal of Intelligent Engineering and Systems, 2010
In the past years there has been an enormous growth in the use of Internet, and new real-time connection- oriented services like streaming technologies and mission-critical transaction-oriented services are in use and new ones are currently emerging. The research on more reliable network becomes an inevitable trend presently.
Yimin Qiu, Jinguang Gu, Hongbing Zhu, Yi Zhou   +3 more
openaire   +1 more source