Results 91 to 100 of about 237,861 (283)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

The optimization of global fault tolerant trajectory for redundant manipulator based on self-motion

open access: yesMATEC Web of Conferences, 2015
The redundancy feature of manipulators provides the possibility for the fault tolerant trajectory planning. Aiming at the completion of the specific task, an algorithm of global fault tolerant trajectory optimization for redundant manipulator based on ...
Zhang Jian   +4 more
doaj   +1 more source

DeSyRe: on-Demand System Reliability

open access: yes, 2013
The DeSyRe project builds on-demand adaptive and reliable Systems-on-Chips (SoCs). As fabrication technology scales down, chips are becoming less reliable, thereby incurring increased power and performance costs for fault tolerance. To make matters worse,
Armato, Antonino   +17 more
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Self-Stabilization, Byzantine Containment, and Maximizable Metrics: Necessary Conditions [PDF]

open access: yes, 2011
Self-stabilization is a versatile approach to fault-tolerance since it permits a distributed system to recover from any transient fault that arbitrarily corrupts the contents of all memories in the system.
Dubois, Swan   +2 more
core   +3 more sources

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu   +10 more
wiley   +1 more source

Demagnetization and Fault-Tolerance Analysis in Dual-Stator Axial-Field Flux-Switching Permanent Magnet Motor

open access: yesIEEE Access
The increasing concerns surrounding demagnetization risk and fault tolerance in direct-drive in-wheel motor applications prompt a detailed investigation.
Fariba Farrokh   +5 more
doaj   +1 more source

Smart Intra-query Fault Tolerance for Massive Parallel Processing Databases

open access: yesData Science and Engineering, 2019
Intra-query fault tolerance has increasingly been a concern for online analytical processing, as more and more enterprises migrate data analytical systems from mainframes to commodity computers.
Yunhong Ji   +4 more
doaj   +1 more source

A fault-tolerant intelligent robotic control system [PDF]

open access: yes
This paper describes the concept, design, and features of a fault-tolerant intelligent robotic control system being developed for space and commercial applications that require high dependability.
Marzwell, Neville I., Tso, Kam Sing
core   +1 more source

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