Results 71 to 80 of about 237,861 (283)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Networking Microcontrollers and Balancing the Load on the Service Servers to Enhance the Fault Tolerance of the IoT Networks

Mathematics
Different types of faults occur in different layers of IoT networks, which affect their fault tolerance. The Controller and Services layers are the weakest links in an IoT network, and any failure in these layers drastically reduces its fault tolerance ...
Sastry Kodanda Rama Jammalamadaka, Bhupati Chokra, Sasi Bhanu Jammalamadaka, Balakrishna Kamesh Duvvuri   +3 more
doaj   +1 more source

Fault location of distribution networks based on multi-source information

Global Energy Interconnection, 2020
In order to promote the development of the Internet of Things (loT), there has been an increase in the coverage of the customer electric information acquisition system (CEIAS).
Wenbo Li, Jianjun Su, Xin Wang, Jiamei Li, Qian Ai   +4 more
doaj   +1 more source

Design of the fault tolerant command and data handling subsystem for ESTCube-1; pp. 222–231 [PDF]

Proceedings of the Estonian Academy of Sciences, 2014
This paper presents the design, implementation, and pre-launch test results of the Command and Data Handling Subsystem (CDHS) for ESTCube-1. ESTCube-1 is a one-unit CubeSat, which will perform an electric solar wind sail experiment.
Kaspars Laizans, Indrek Sünter, Karlis Zalite, Henri Kuuste, Martin Valgur, Karl Tarbe, Viljo Allik, Georgi Olentšenko, Priit Laes, Silver Lätt, Mart Noorma   +10 more
doaj   +1 more source

Unidirectional Quorum-based Cycle Planning for Efficient Resource Utilization and Fault-Tolerance

, 2016
In this paper, we propose a greedy cycle direction heuristic to improve the generalized $\mathbf{R}$ redundancy quorum cycle technique. When applied using only single cycles rather than the standard paired cycles, the generalized $\mathbf{R}$ redundancy ...
Kleinheksel, Cory J., Somani, Arun K.
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Distributed intelligent robotics : research & development in fault-tolerant control and size/position identification : a thesis presented in partial fulfilment of the requirements for the degree of Master of Engineering in Computer Systems Engineering at Massey University [PDF]

, 2002
This thesis presents research conducted on aspects of intelligent robotic systems. In the past two decades, robotics has become one of the most rapidly expanding and developing fields of science.
Subramaniam, Karthikeya Krishna
core  

Beyond Optimal Fault Tolerance

The optimal fault-tolerance achievable by any protocol has been characterized in a wide range of settings. For example, for state machine replication (SMR) protocols operating in the partially synchronous setting, it is possible to simultaneously guarantee consistency against $α$-bounded adversaries (i.e., adversaries that control less than an $α ...
Lewis-Pye, Andrew, Roughgarden, Tim
openaire   +4 more sources

Fault-tolerant compass codes

Physical Review A, 2020
We study a class of gauge fixings of the Bacon-Shor code at the circuit level, which includes a subfamily of generalized surface codes. We show that for these codes, fault tolerance can be achieved by direct measurements of the stabilizers. By simulating our fault-tolerant scheme under biased noise, we show the possibility of optimizing the performance
Shilin Huang, Kenneth R. Brown
openaire   +4 more sources