Results 61 to 70 of about 236,153 (262)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Adaptive Online Fault Diagnosis in Autonomous Robot Swarms

open access: yesFrontiers in Robotics and AI, 2018
Previous work has shown that robot swarms are not always tolerant to the failure of individual robots, particularly those that have only partially failed and continue to contribute to collective behaviors.
James O'Keeffe   +3 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Design of the fault tolerant command and data handling subsystem for ESTCube-1; pp. 222–231 [PDF]

open access: yesProceedings of the Estonian Academy of Sciences, 2014
This paper presents the design, implementation, and pre-launch test results of the Command and Data Handling Subsystem (CDHS) for ESTCube-1. ESTCube-1 is a one-unit CubeSat, which will perform an electric solar wind sail experiment.
Kaspars Laizans   +10 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Networking Microcontrollers and Balancing the Load on the Service Servers to Enhance the Fault Tolerance of the IoT Networks

open access: yesMathematics
Different types of faults occur in different layers of IoT networks, which affect their fault tolerance. The Controller and Services layers are the weakest links in an IoT network, and any failure in these layers drastically reduces its fault tolerance ...
Sastry Kodanda Rama Jammalamadaka   +3 more
doaj   +1 more source

Fault location of distribution networks based on multi-source information

open access: yesGlobal Energy Interconnection, 2020
In order to promote the development of the Internet of Things (loT), there has been an increase in the coverage of the customer electric information acquisition system (CEIAS).
Wenbo Li   +4 more
doaj   +1 more source

What does fault tolerant Deep Learning need from MPI?

open access: yes, 2017
Deep Learning (DL) algorithms have become the de facto Machine Learning (ML) algorithm for large scale data analysis. DL algorithms are computationally expensive - even distributed DL implementations which use MPI require days of training (model learning)
Amatya, Vinay   +3 more
core   +1 more source

Fault-Tolerant Sequential Scan [PDF]

open access: yesTheory of Computing Systems, 2007
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Flocchini, Paola   +2 more
openaire   +2 more sources

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