Results 171 to 180 of about 466,472 (359)
Cortical Response to Acute Implantation of the Utah Optrode Array in Macaque Cortex
Advanced Healthcare Materials, EarlyView.Delivering light deep into the brain over a large volume while causing minimal tissue damage is a major challenge for non‐human primate optogenetics. This study evaluates Utah Optrode Array designs in vivo, revealing how changes in shank geometry, surface texture, and insertion parameters minimize acute damage—offering a path toward high‐precision ...
Adrián Villamarin‐Ortiz +8 more
wiley +1 more source
Norbornene Homopolymerization Limits Cell Spreading in Thiol–Ene Photoclick Hydrogels
Advanced Healthcare Materials, EarlyView.Thiol–norbornene click reactions are often used in the development of cell‐permissive 3D hydrogels. However, ene–ene crosslinks in other thiol–ene systems are known to limit permissivity. This study demonstrates the negative effects of norbornene homopolymerization on 3D cell spreading and circumvents the issue by modulating polymer degree of ...
James L. Gentry, Steven R. Caliari
wiley +1 more source
Integrating Insults: Using Fault Tree Analysis to Guide Schizophrenia Research across Levels of Analysis. [PDF]
Front Hum Neurosci, 2015 MacDonald Iii AW +3 more
europepmc +1 more source
Beyond Bioactive Glass Composition: Using Morphology to Improve in Vitro and in Vivo Performance
Advanced Healthcare Materials, EarlyView.Bioactive glasses can easily be shaped into granules, spheres, discs, fibers, or three‐dimensional scaffolds. The resulting morphology not only affects handling properties; it has a direct influence on various glass properties, including results of acellular immersion experiments or in vitro studies with cells or bacteria, but also on in vivo ...
Meixin Su +5 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This study presents a bone‐on‐a‐chip platform incorporating TPMS scaffolds to study geometry‐dependent osteogenesis under dynamic flow. By tuning pore shape and solidity, it precisely controls mechanical cues, revealing how topological features and shear stress affect osteogenic differentiation and matrix formation.
Donggyu Kim +5 more
wiley +1 more source
Advancing Dynamic Fault Tree Analysis - Get Succinct State Spaces Fast and Synthesise Failure Rates [PDF]
, 2016 Matthias Volk +2 more
openalex +1 more source
AI‐Assisted Design and Evaluation of SLM‐Ti64 Implants for Enhanced Bone Regeneration
Advanced Healthcare Materials, EarlyView.AI‐driven simulations of biological healing, combining biomechanical modeling and machine learning, enable personalized orthopedic treatments. By decoding healing patterns influenced by implants and patient‐specific factors, this approach advances fracture repair understanding, optimizes implant design, and supports precision medicine and sustainable ...
Muhammad Usama Zaheer +3 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This work presents a low‐cost, reagent‐free point‐of‐care biosensor integrating redox‐active polyphenol red molecularly imprinted polymers (pPhR MIPs) on highly porous gold (HPG) electrodes for ultrasensitive detection of phosphorylated tau 181 (p‐Tau 181), an Alzheimer’s disease biomarker, in undiluted biofluids.
Sudhaunsh Deshpande +4 more
wiley +1 more source