Results 191 to 200 of about 891,536 (298)

Correction: Flora and fauna: how nonhuman species interact with natural and man-made EMF at ecosystem levels and public policy recommendations. [PDF]

Front Public Health
Levitt BB, Lai HC, Manville AM, Scarato T.   +3 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Paleogenomic evidence on the temporal continuity of indigenous goat exploitation in the Canary Islands. [PDF]

iScience
Díaz-Pérez C, Santana J, Daly KG, Ordóñez AC, Serrano JG, Armas-Quintana SB, Vacas-Fumero E, Brito-Mayor A, Gilson SP, Morales J, Marrero Salas E, Hernández JC, Alberto V, Moreno M, Günther T, Morell Miranda P, Valdiosera C, Hernández M, Arnay M, Fregel R.   +19 more
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Circulation and overwintering of Usutu virus lineages in north-eastern Spain: A one health perspective (2021-2025). [PDF]

One Health
Leka A, Gardela J, Obón E, Pifarré M, Martínez MJ, Navero-Castillejos J, Casals R, Solé A, Busquets N.   +8 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Author Correction: Healthy forests safeguard traditional wild meat food systems in Amazonia. [PDF]

Nature
Antunes AP, de Araujo Lima Constantino P, Fa JE, Fa JE, Munari DP, Morcatty TQ, Jacob MCM, Nelson BW, Cassino MF, Carvalho EAR, Ickowitz A, Coad L, Bodmer RE, Mayor P, Richard-Hansen C, Valsecchi J, Campos-Silva JV, Pezzuti JCB, Aparício M, von Muhlen EM, Oliveira MA, de Paula MJ, Pimenta NC, de Mattos Vieira MAR, Santos Junior MA, Nunes AV, Boubli JP, Suruí LMG, Paumari ECS, Paumari AVC, Paumari JLVS, Paumari GC, Katukina APLR, Baniwa D, Baniwa VSM, Baniwa WSL, Baniwa AOF, Baniwa AB, Baniwa IJS, Waura Y, Silvestre Apurinã J, Apurinã VSS, Tikuna JOG, Tikuna EPAL, Kaxinauá JL, Kuikuro KB, Penaforth Kaixana JT, Rebelo GH, Torquato D, Apurinã VSF, Antúnez M, Perez-Peña PE, Fang TG, Puertas PE, Aquino RM, Maranhão L, Longin G, Lopes CKM, El Bizri HR.   +58 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Well-Known, Misidentified, or Unnamed? A DNA Barcode-Based Reassessment of the Lepidoptera Fauna of Cyprus Supported by Morphology. [PDF]

Insects
Huemer P, Özden Ö, Rennwald E, Barton I, Junnilainen J, Hausmann A, van Nieukerken EJ, Hebert PDN.   +7 more
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source