Results 201 to 210 of about 279,410 (290)

Collaborative Conservation Genetics of Cryptic Reptile Taxa From Northern Australia. [PDF]

Ecol Evol
Campbell BL, Rangers Y, Rangers YM, Rangers N, Learning on Country – Laynhapuy Homelands School, Learning on Country – Shepherdson College, Dudaniec RY, Moritz C, Fenker J, Ens E.   +9 more
europepmc   +1 more source

Deep-sea gas hydrate mounds and chemosynthetic fauna discovered at 3640 m on the Molloy Ridge, Greenland Sea. [PDF]

Nat Commun
Panieri G, Copley JT, Linse K, Nye V, Ramirez-Llodra E, Argentino C, Ferré B, Arctic Deep - Extreme24 consortium, Rogers AD.   +8 more
europepmc   +1 more source

Discovery of White Sea assemblage fossils from Laurentia. [PDF]

Sci Adv
Evans SD, Sperling EA, Lau KV, Strauss JV.   +3 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Isolated mycobiota from carcasses of wild animals run over on Highway 493 in Seropédica, Rio de Janeiro, Brazil. [PDF]

Braz J Vet Med
Pardão CAA, da Silva JF, Pereira JASM, Bonci MM, Matias CAR, de Oliveira ÁA.   +5 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Beneath the canopy, beneath the ground: how surface microhabitats shape cave communities. [PDF]

PeerJ
Oliveira MPA, Ferreira RL.
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Paleogenomic evidence on the temporal continuity of indigenous goat exploitation in the Canary Islands. [PDF]

iScience
Díaz-Pérez C, Santana J, Daly KG, Ordóñez AC, Serrano JG, Armas-Quintana SB, Vacas-Fumero E, Brito-Mayor A, Gilson SP, Morales J, Marrero Salas E, Hernández JC, Alberto V, Moreno M, Günther T, Morell Miranda P, Valdiosera C, Hernández M, Arnay M, Fregel R.   +19 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source