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Comparative Genomics Unveils Regionalized Evolution of the Faustovirus Genomes [PDF]

open access: yesViruses, 2020
Faustovirus is a recently discovered genus of large DNA virus infecting the amoeba Vermamoeba vermiformis, which is phylogenetically related to Asfarviridae.
Guillaume Blanc   +2 more
exaly   +7 more sources

Faustovirus E12 Transcriptome Analysis Reveals Complex Splicing in Capsid Gene [PDF]

open access: yesFrontiers in Microbiology, 2018
Faustoviruses are the first giant viruses of amoebae isolated on Vermamoeba vermiformis. They are distantly related to African swine fever virus, the causative agent of lethal hemorrhagic fever in domestic pigs. Structural studies have shown the presence
Philippe Colson   +2 more
exaly   +8 more sources

Asfarviruses and Closely Related Giant Viruses [PDF]

open access: yesViruses, 2023
Acanthamoeba polyphaga mimivirus, so called because of its “mimicking microbe”, was discovered in 2003 and was the founding member of the first family of giant viruses isolated from amoeba.
Bernard La Scola   +2 more
exaly   +4 more sources

Engineering a Virus‐Derived X Family DNA Polymerase FvPolX for de novo DNA Synthesis [PDF]

open access: yesAdvanced Science
Enzymatic de novo DNA synthesis has gained increasing attention over the past decades, having emerged as a hotspot in synthetic biology. However, current research remains largely focused on animal‐derived X‐family DNA polymerases (PolXs), such as the ...
Chengjie Zhang, Lei Du, Shengying Li
doaj   +3 more sources

Clandestinovirus: A Giant Virus With Chromatin Proteins and a Potential to Manipulate the Cell Cycle of Its Host Vermamoeba vermiformis [PDF]

open access: yesFrontiers in Microbiology, 2021
For several decades, the vast world of DNA viruses has been expanding constantly. Various discoveries in this field have broadened our knowledge and revealed that DNA viruses encode many functional features, which were once thought to be exclusive to ...
Bernard La Scola   +2 more
exaly   +4 more sources

Putative Promoter Motif Analyses Reinforce the Evolutionary Relationships Among Faustoviruses, Kaumoebavirus, and Asfarvirus [PDF]

open access: yesFrontiers in Microbiology, 2018
Putative promoter motifs have been described in viruses belonging to the nucleocytoplasmic large DNA viruses (NCLDVs) group; however, few studies have been conducted to search for promoter sequences in newly discovered amoebal giant viruses.
Abrahão Js   +2 more
exaly   +4 more sources

Giant virus vs amoeba: fight for supremacy [PDF]

open access: yesVirology Journal, 2019
Since the discovery of mimivirus, numerous giant viruses associated with free-living amoebae have been described. The genome of giant viruses can be more than 2.5 megabases, and virus particles can exceed the size of many bacteria.
Bernard La Scola   +2 more
exaly   +4 more sources

Usurpativirus massiliensis, a new giant virus related to clandestinovirus [PDF]

open access: yesVirology Journal
Giant virus discovery in 2003 revolutionized the virus paradigm. In 2015, we introduced a new host, Vermamoeba vermiformis, that led to the discovery of Faustovirus, Orpheovirus and two giant viruses (Clandestinovirus and a faustovirus) having distinct ...
Julien Andreani   +6 more
doaj   +2 more sources

Integrative genomic analyses support the division of the extended Asfarviridae clade into multiple viral families [PDF]

open access: yesJournal of Virology
Giant viruses continue to challenge our understanding of virology, blurring boundaries of what a virus can be. The so-called “extended Asfarviridae”— such as African swine fever virus, faustovirus, kaumoebavirus, pacmanvirus, and AbALV—has long puzzled ...
Thiago Mendonça-Santos   +2 more
doaj   +2 more sources

Diversity of Giant Viruses Infecting Vermamoeba vermiformis [PDF]

open access: yesFrontiers in Microbiology, 2022
The discovery of Acanthamoeba polyphaga mimivirus in 2003 using the free-living amoeba Acanthamoeba polyphaga caused a paradigm shift in the virology field.
Khalil Geballa-Koukoulas   +4 more
doaj   +2 more sources

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