Faustovirus-Like Asfarvirus in Hematophagous Biting Midges and Their Vertebrate Hosts [PDF]
Faustovirus, a new Asfarviridae-related giant virus, was recently isolated in Vermamoeba vermiformis, a protist found in sewage water in various geographical locations and occasionally reported in human eye infection cases.
Bernard La Scola +2 more
exaly +5 more sources
Biochemical characterization of mRNA capping enzyme from Faustovirus [PDF]
Abstract The mammalian mRNA 5’ cap structures play important roles in cellular processes such as nuclear export, efficient translation, and evading cellular innate immune surveillance and regulating 5’- mediated mRNA turnover. Hence, installation of the proper 5’ cap is crucial in therapeutic applications of synthetic mRNA.
Jackson Buss +2 more
exaly +4 more sources
The Kaumoebavirus LCC10 Genome Reveals a Unique Gene Strand Bias among “Extended Asfarviridae” [PDF]
Kaumoebavirus infects the amoeba Vermamoeba vermiformis and has recently been described as a distant relative of the African swine fever virus. To characterize the diversity and evolution of this novel viral genus, we report here on the isolation and ...
Khalil Geballa-Koukoulas +3 more
doaj +2 more sources
"More" Artificial mRNAs: Beyond the Art of Nature. [PDF]
Inspired by nature yet transcending it, synthetic mRNA is being redesigned beyond the canonical architecture. This review highlights emerging forms—circular, branched, and self‐amplifying mRNAs—that expand stability, persistence, and functional control, illustrating how artificial mRNA is evolving into a new medium for programmable biological ...
Cui Y, Fukui M, Ohno H, Saito H.
europepmc +2 more sources
Faustoviruses: Comparative Genomics of New Megavirales Family Members
An emerging interest for the giant virus discovery process, genome sequencing and analysis has allowed an expansion of the number of known Megavirales members. Using the protist Vermamoeba sp. as cell support, a new giant virus named Faustovirus has been
Bernard La Scola +2 more
exaly +3 more sources
In-depth analysis of the replication cycle of Orpheovirus
Background After the isolation of Acanthamoeba polyphaga mimivirus (APMV), the study and search for new giant viruses has been intensified. Most giant viruses are associated with free-living amoebae of the genus Acanthamoeba; however other giant viruses ...
Erik V S Reis +2 more
exaly +2 more sources
Structural Insights into the Assembly of the African Swine Fever Virus Inner Capsid [PDF]
Ye Xiang, Haining Li
exaly +2 more sources
Trapping the Enemy: Vermamoeba vermiformis Circumvents Faustovirus Mariensis Dissemination by Enclosing Viral Progeny inside Cysts. [PDF]
Understanding how viruses of microbes interact with its hosts is not only important from a basic scientific point of view but also for a better comprehension of the evolution of life. Studies involving large and giant viruses have revealed original and outstanding mechanisms concerning virus-host relationships.
Borges I +8 more
europepmc +6 more sources
Murine Norovirus: Additional Protocols for Basic and Antiviral Studies
Abstract Murine norovirus (MNV) is a positive‐sense, plus‐stranded RNA virus in the Caliciviridae family. Viruses in this family replicate in the intestine and are transmitted by the fecal‐oral route. MNV is related to the human noroviruses, which cause the majority of nonbacterial gastroenteritis worldwide.
Christiane E. Wobus +15 more
wiley +1 more source
High‐performance macromolecular data delivery and visualization for the web
This article provides a survey of available web services and tools for data delivery and visualization of macromolecular structures.Biomacromolecular structural data make up a vital and crucial scientific resource that has grown not only in terms of its amount but also in its size and complexity.
David Sehnal +6 more
wiley +1 more source

