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Phylogenetic, clinical, pathological and epidemiological characterization of feline coronavirus infections in cats, in Istanbul [PDF]

open access: yesFrontiers in Veterinary Science
IntroductionFeline coronavirus (FCoV) is a widespread viral infection affecting domestic and wild cats globally, with higher prevalence in young cats and multi-cat environments.MethodsIn this study, a total of 208 clinical samples (blood, fecal, ascitic ...
Gulay Yuzbasioglu Ozturk   +19 more
doaj   +2 more sources

Serine protease-driven entry and S2 ' cleavage flexibility of feline coronavirus during feline enterocyte infections. [PDF]

open access: yesPLoS Pathogens
Coronaviruses not only hijack host cells to serve as viral factories but also exploit host proteolytic systems to activate their spike (S) protein, the key glycoprotein mediating receptor binding and membrane fusion.
Bixia Chen   +5 more
doaj   +2 more sources

Rethinking the drivers of coronavirus virulence and pathogenesis; toward an understanding of the dynamic world of mutations, indels, and recombination within the alphacoronaviruses [PDF]

open access: yesmBio
Alphacoronaviruses are widespread but understudied in comparison to betacoronaviruses. Within the alphacoronaviruses is the species Alphacoronavirus-1, which comprises distinct viruses of cats, dogs, and pigs, along with a separate species that infects ...
Ximena A. Olarte-Castillo   +4 more
doaj   +2 more sources

Development of a yeast-based CRISPR genome editing system for feline coronavirus [PDF]

open access: yesFrontiers in Microbiology
IntroductionFeline infectious peritonitis (FIP), caused by feline coronavirus (FCoV), is a highly lethal disease characterized by systemic organ infection in cats. Current challenges of FIP include the absence of definitive diagnostic criteria, effective
Xiaohu Zhang   +4 more
doaj   +2 more sources

Establishment of one-step duplex TaqMan real-time PCR for detection of feline coronavirus and panleukopenia virus [PDF]

open access: yesApplied Microbiology and Biotechnology
A comparative genomic analysis of feline coronavirus (FCoV) and feline panleukopenia virus (FPLV) was performed. Based on the conserved regions of the two viruses, specific probes and real-time PCR (qPCR) primers were designed, and a duplex TaqMan qPCR ...
Zhe Liu   +9 more
doaj   +2 more sources

Feline Coronavirus in Northern Vietnam: Genetic Detection and Characterization Reveal Predominance of Type I Viruses [PDF]

open access: yesViruses
This study was conducted to identify the molecular and biological characteristics of the collected feline coronavirus (FCoV) strains in northern Vietnam.
Hieu Van Dong   +3 more
doaj   +2 more sources

In Vitro Evaluation of Aryl Hydrocarbon Receptor Involvement in Feline Coronavirus Infection [PDF]

open access: yesViruses
Feline coronavirus (FCoV) is an alphacoronavirus (αCoV) that causes moderate or chronic asymptomatic infection in cats. However, in a single infected cat, FCoV can modify its cellular tropism by acquiring the ability to infect macrophages, resulting in ...
Luca Del Sorbo   +15 more
doaj   +2 more sources

Whole genome characterization of feline coronaviruses in Thailand: evidence of genetic recombination and mutation M1058L in pathotype switch [PDF]

open access: yesFrontiers in Veterinary Science
Feline coronavirus (FCoV) is a significant pathogen that infects the feline population worldwide. FCoV can cause mild enteric disease and a fatal systemic disease called feline infectious peritonitis (FIP). In this study, a cross-sectional survey of FCoV
Eaint Min Phyu   +18 more
doaj   +2 more sources

Detection of Feline Coronavirus RNA in Cats with Feline Infectious Peritonitis and Their Housemates [PDF]

open access: yesViruses
Feline coronavirus (FCoV), the causative agent behind feline infectious peritonitis (FIP), is one of the biggest infectious threats to feline health.
Phoenix M. Shepherd   +4 more
doaj   +2 more sources

Application of versatile reverse genetics system for feline coronavirus [PDF]

open access: yesMicrobiology Spectrum
Feline infectious peritonitis (FIP) is a fatal disease caused by feline coronavirus (FCoV). Although multiple gene mutations in FCoV likely account for FIP pathogenesis, molecular studies for FCoV have been limited due to the lack of a suitable reverse ...
Izumi Kida   +5 more
doaj   +2 more sources

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