Results 41 to 50 of about 2,135 (155)

Natural FCoV infection: Cats with FIP exhibit significantly higher viral loads than healthy infected cats [PDF]

Journal of Feline Medicine and Surgery, 2006
Natural feline coronavirus (FCoV) infection has been shown to not only induce intestinal infection with viral shedding, but also systemic infection which either remains without clinical signs or leads to feline infectious peritonitis (FIP). As systemic infection is not the key event in the development of FIP, the question arises as to whether a ...
Kipar, Anja, Baptiste, Keith Edward, Barth, Andreas, Reinacher, Manfred   +3 more
openaire   +3 more sources

Serological Investigation on the Presence of Feline Coronavirus (FCoV) and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Domestic Cats Living with COVID-19 Positive Owners in the UAE, 2022

Animals, 2023
Feline coronavirus (FCoV) is widely circulating among domestic cats (Felis catus). The zoonotic origin of the emerged severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and the biological characteristics of CoVs, including the ability to cross ...
Mohamed El-Tholoth, Mahmoud Hussein, Dina Mohammed, Majed Al-Rasheedi, Hamad Al-Qubaisi, Abdullah Al-Blooshi, Mohammed Al-Ahbabi, Zayed Al-Dhaheri, Khalifa Al-Blooshi, Majd Al-Herbawi, Eman A. Abo Elfadl, Rabiha Seboussi   +11 more
doaj   +1 more source

FCoV Viral Sequences of Systemically Infected Healthy Cats Lack Gene Mutations Previously Linked to the Development of FIP [PDF]

Pathogens, 2020
Feline Infectious Peritonitis (FIP)—the deadliest infectious disease of young cats in shelters or catteries—is induced by highly virulent feline coronaviruses (FCoVs) emerging in infected hosts after mutations of less virulent FCoVs. Previous studies have shown that some mutations in the open reading frames (ORF) 3c and 7b and the spike (S) gene have ...
Lutz, Mirjam, Steiner, Aline R, Cattori, Valentino, Hofmann-Lehmann, Regina, Lutz, Hans, Kipar, Anja, Meli, Marina L   +6 more
openaire   +4 more sources

The Paradox of Feline Coronavirus Pathogenesis: A Review

Advances in Virology, 2011
Feline coronavirus (FCoV) is an enveloped single-stranded RNA virus, of the family Coronaviridae and the order Nidovirales. FCoV is an important pathogen of wild and domestic cats and can cause a mild or apparently symptomless enteric infection ...
Luciana Wanderley Myrrha, Fernanda Miquelitto Figueira Silva, Ethel Fernandes de Oliveira Peternelli, Abelardo Silva Junior, Maurício Resende, Márcia Rogéria de Almeida   +5 more
doaj   +1 more source

Evaluation of Association between Blood Phenotypes A, B and AB and Feline Coronavirus Infection in Cats

Pathogens, 2022
Cats are susceptible to feline coronavirus (FCoV), a highly contagious virus with fecal–oral transmission. In people, susceptibility to coronavirus infection, such as SARS-CoV infection, has been associated with the ABO blood group, with individuals with
Eva Spada, Alice Carrera Nulla, Roberta Perego, Luciana Baggiani, Daniela Proverbio   +4 more
doaj   +1 more source

Antiviral activity of Vigna radiata extract against feline coronavirus in vitro

Veterinary Quarterly
Feline infectious peritonitis (FIP) is a fatal illness caused by a mutated feline coronavirus (FCoV). This disease is characterized by its complexity, resulting from systemic infection, antibody-dependent enhancement (ADE), and challenges in accessing ...
Ai-Ai Chou, Chung-Hui Lin, Yen-Chen Chang, Hui-Wen Chang, Yi-Chen Lin, Chia-Chen Pi, Yao-Ming Kan, Hao-Fen Chuang, Hui-Wen Chen   +8 more
doaj   +1 more source

Quasispecies composition and phylogenetic analysis of feline coronaviruses (FCoVs) in naturally infected cats

FEMS Immunology & Medical Microbiology, 2003
Quasispecies composition and tissue distribution of feline coronaviruses (FCoVs) were studied in naturally infected cats. The genomic complexity of FCoVs was investigated using single-strand conformational polymorphism (SSCP) analysis of N and ORF7b amplicons, and the evolutionary process was investigated by sequence-based phylogenetic analysis.
Battilani M., Coradin T., Scagliarini A., Ciulli S., Ostanello F., Prosperi S., Morganti L.   +6 more
openaire   +2 more sources

Molecular detection using hybridization capture and next-generation sequencing reveals cross-species transmission of feline coronavirus type-1 between a domestic cat and a captive wild felid

Microbiology Spectrum
Feline coronavirus (FCoV) infection normally causes mild or subclinical signs and is common in domestic cats. However, in some cats, FCoV infection can also lead to the development of feline infectious peritonitis (FIP)—a typically lethal disease.
Ximena A. Olarte-Castillo, Laura B. Goodman, Gary R. Whittaker   +2 more
doaj   +1 more source

Ionophore Antibiotics Inhibit Type II Feline Coronavirus Proliferation In Vitro

Viruses, 2022
Feline coronaviruses (FCoVs) infect cats worldwide and cause severe systemic diseases, such as feline infectious peritonitis (FIP). FIP has a high mortality rate, and drugs approved by the Food and Drug Administration have been ineffective for the ...
Yoshikazu Tanaka, Eri Tanabe, Yuki Nonaka, Mitsuki Uemura, Tsuyoshi Tajima, Kazuhiko Ochiai   +5 more
doaj   +1 more source

Coronavirus Nsp3 Hijacks CLTC to Modulate Autophagosome Nucleation for Promoting DMV Formation and Viral Replication

Advanced Science, EarlyView.
In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu, Hang Li, Peng Liu, Zhe Jiao, Ding Zhang, Zhelin Su, Sai Niu, Jintao Zhang, Yuejun Shi, Guiqing Peng   +9 more
wiley   +1 more source