Results 141 to 150 of about 812,951 (357)
Uncovering Data Across Continua: An Introduction to Functional Data Analysis [PDF]
In a world increasingly awash with data, the need to extract meaningful insights from data has never been more crucial. Functional Data Analysis (FDA) goes beyond traditional data points, treating data as dynamic, continuous functions, capturing ever-changing phenomena nuances. This article introduces FDA, merging statistics with real-world complexity,
arxiv
Ovarian cancer's high recurrence and therapy resistance demand new strategies. A high‐throughput drug screening pipeline using 3D spheroids, which showed poor concordance with 2D models, identified rapamycin as a promising candidate. In combination with cisplatin, rapamycin demonstrated significant in vitro and in vivo efficacy, highlighting the ...
Nazanin Karimnia+9 more
wiley +1 more source
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto+2 more
wiley +1 more source
Motor‐Free Soft Robots for Cancer Detection, Surgery, and In Situ Bioprinting
Novel motor‐free soft robots for cancer detection, surgery, and in situ bioprinting–are presented. This master‐slave system is constructed from soft fibrous syringe architectures, removing the need for electrical motors and complex control mechanisms, while reducing the physical tremors.
Chi Cong Nguyen+17 more
wiley +1 more source
Relationship between safety data and biocontainment design in the environmental assessment of fermentation organisms — An FDA perspective [PDF]
Richard A. Jones, John C. Matheson
openalex +1 more source
We thoroughly analyze at the bosonic level, in the framework of Free Differential Algebras (FDA), the role of 2-form potentials setting in particular evidence the precise geometric formulation of the anti-Higgs mechanism giving mass to the tensors.
Andrianopoli, Laura+2 more
core
A novel hydrogel (HLBP) incorporating natural polysaccharides from goji berries is developed to enhance diabetic bone defect healing. The hydrogel efficiently scavenges ROS, improves osteogenic differentiation, and promotes in vivo bone regeneration. This strategy offers a biocompatible and localized approach, overcoming the challenges of traditional ...
Wenjie Zhong+9 more
wiley +1 more source
FDA arthritis advisory committee meeting: Expanded role for committee members; guidelines on analgesics [PDF]
Harold E. Paulus
openalex +1 more source
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq+4 more
wiley +1 more source