Results 171 to 180 of about 812,951 (357)
Advanced Materials, EarlyView.Base editing using nanoneedles efficiently corrects pathogenic variants in the type VII collagen gene of primary fibroblasts from patients with recessive dystrophic epidermolysis bullosa. Nanoneedle editing induces minimal and reversible transcriptional perturbations while restoring the production and secretion of functional type VII collagen.
Salman Ahmad Mustfa +10 more
wiley +1 more source
Restriction of Ethylene Oxide and it Reaction Products Porposed by FDA
, 1979 Takuma Ōba
openalex +2 more sources
Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting
Advanced Materials, EarlyView.CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu +4 more
wiley +1 more source
Off‐The‐Shelf Multivalent Nanoconjugate Cancer Vaccine Rescues Host Immune Response against Melanoma
Advanced Materials, EarlyView.A star‐shaped cross‐linked polyglutamate (StCl) nanocarrier delivers melanoma‐associated peptide antigens via redox‐responsive linkers, inducing lymph node‐targeted antigen presentation. The nanoconjugate activates dendritic cells, promotes effector T‐cell responses, and enables tumor regression even in humanized patient‐derived preclinical models ...
Liane IF Moura +19 more
wiley +1 more source
Secure Wireless Communications via Frequency Diverse Arrays [PDF]
arXivA novel frequency diverse array (FDA)-assisted secure transmission framework is proposed, which leverages additional frequency offsets to enhance physical layer security. Specifically, an FDA-assisted wiretap channel is considered, where the transmit beamforming and frequency offsets at each antenna are jointly optimized.
arxiv
Fault detection and accommodation testing on an F100 engine in an F-15 airplane [PDF]
The fault detection and accommodation (FDA) methodology for digital engine-control systems may range from simple comparisons of redundant parameters to the more complex and sophisticated observer models of the entire engine system.
Baer-Riedhart, J. L. +2 more
core +1 more source
Advanced Materials, EarlyView.Upconversion nanoparticle‐covalent organic framework core–shell particles provide enhanced contrast for optoacoustic imaging by leveraging the optical absorption of upconversion luminescence within the covalent organic framework matrix. Beyond their role as contrast agents, these particles enable customizable therapeutic agent loading and release, as ...
Dong Wook Kim +8 more
wiley +1 more source