Results 171 to 180 of about 1,107,201 (376)
Advanced Functional Materials, EarlyView.Liquid crystalline inverted lipid phases and reverse micelles are self‐assembled lipid nanostructures that enhance the solubility, stability, and delivery of diverse therapeutics. This review integrates their physicochemical principles, formulation strategies, drug loading mechanisms, and biomedical applications, highlighting their growing ...
Numan Eczacioglu +3 more
wiley +1 more source
When AI Meets the FDA: An Evaluation of Large Language Models Performance in Regulatory and Clinical Trial Data Extraction, Synthesis, and Analysis [PDF]
K Bukhari +7 more
openalex +1 more source
Advanced Functional Materials, EarlyView.Herein, an RBC membrane‐derived nanoparticle (CMN‐ICG) is engineered to efficiently deliver a sonosensitizing agent, indocyanine green (ICG), for sonotherapy of hepatocellular carcinoma (HCC). CMN‐ICG exhibits excellent cytocompatibility, significantly enhances hepatocyte uptake, and produces excessive reactive oxygen species (ROS) upon ultrasound ...
Alap Ali Zahid +6 more
wiley +1 more source
Advanced Functional Materials, EarlyView.PREdicting LNP In Vivo Efficacy (PRELIVE) framework enables the prediction of lipid nanoparticle (LNPs) organ‐specific delivery through dual modeling approaches. Composition‐based models using formulation parameters and protein corona‐based models using biological fingerprints both achieve high predictive accuracy across multiple organs.
Belal I. Hanafy +3 more
wiley +1 more source
Journal of Comparative Effectiveness Research, 2023 Ben Bray, Sreeram V Ramagopalan
doaj +1 more source
FDA orphan drug designations for lysosomal storage disorders – a cross sectional analysis [PDF]
, 2020 Sven F. Garbade +7 more
openalex +1 more source
Drug‐Free Thrombolysis Mediated by Physically Activated Micro/Nanoparticles
Advanced Functional Materials, EarlyView.Overview of particle‐mediated thrombolytic effects (thermal, mechanical, and chemical) and their activating physical stimuli (light, ultrasound, and magnetic field) in drug‐free thrombolysis. ABSTRACT Thrombus‐associated disorders rank among the world's leading causes of death, with ischemic heart disease and stroke as the main contributors.
Pierre Sarfati +2 more
wiley +1 more source
Contraceptive Potential of FDA Approved Excipient N,N-Dimethylacetamide
, 2020 Nupur Khera
openalex +1 more source
Properties of FDA-approved Small Molecule Protein Kinase Inhibitors: A 2023 Update.
Pharmacological Research, 2022 R. Roskoski
semanticscholar +1 more source