Results 71 to 80 of about 812,951 (357)
United States' federal regulation of e-Cigarettes
Hail Journal of Health Sciences, 2020 The consumption of e-cigarettes has rapidly increased in recent years. This has generated extensive debates and controversies among the public health community, businesses, policy-makers, and consumers. In 2014, the U.S. Food and Drug Administration (FDA)
Badr S Alnasser
doaj +1 more source
Decision Analysis and FDA Drug Review: A Proposal for Shadow Advisory Committees [PDF]
, 1995 The FDA seems to acknowledge that sometimes different standards of proof for assessing drug efficacy should be used. Dr. Mendeloff thus proposes a methodology that might illuminate the FDA\u27s decision-making and help better to assess its ...
Mendeloff, John M.
core +1 more source
Molecular Oncology, EarlyView.Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda +3 more
wiley +1 more source
Non-linear realizations and invariant action principles in higher gauge theory [PDF]
arXiv, 2023 We propose an extension of the formalism developed by Stelle-West and Grignani-Nardelli to the case of FDAs. We first consider the case of FDAs carrying one $p$-form extension and no non-trivial cohomology. We show that it is possible to define large gauge transformations as a direct extension of the large transformations induced by their Lie ...
arxiv
mSphereWhole-cell pertussis (wP) vaccines introduced in the 1940s led to a dramatic reduction of pertussis incidence and are still widely used in low- and middle-income countries (LMICs) worldwide.
Parul Kapil +7 more
doaj +1 more source
ASSESSMENT OF MOUSE EMBRYO VIABILITY BY ESTERASIC ACTIVITY DETECTION
Scientific Papers Animal Science and Biotechnologies, 2023 In order to evaluate the esterasic activity within the viable embryos we used the Fluorescein diacetate (FDA) staining test. For staining was used a 0.5 mg/ml FDA stock solution. The embryos were recovered at 48 hours post coitus from superovulated Swiss
ALEXANDRA BOLEMAN +3 more
doaj
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
Fisher and Kernel Fisher Discriminant Analysis: Tutorial [PDF]
arXiv, 2019 This is a detailed tutorial paper which explains the Fisher discriminant Analysis (FDA) and kernel FDA. We start with projection and reconstruction. Then, one- and multi-dimensional FDA subspaces are covered. Scatters in two- and then multi-classes are explained in FDA. Then, we discuss on the rank of the scatters and the dimensionality of the subspace.
arxiv
The need for a system view to regulate artificial intelligence/machine learning-based software as medical device [PDF]
, 2020 Artificial intelligence (AI) and Machine learning (ML) systems in medicine are poised to significantly improve health care, for example, by offering earlier diagnoses of diseases or recommending optimally individualized treatment plans.
Babic, Boris +3 more
core +3 more sources
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source