Results 251 to 260 of about 509,208 (305)

Leveraging genomic and transcriptomic data of diverse ancestry to uncover mechanisms of psychiatric risk in the adult and developing brain. [PDF]

Nat Commun
Jajoo A, Balakundi V, Chatzinakos C, Aruldass A, Wen C, Kolmans IGC, Iatrou A, Kleinman JE, Ressler KJ, Bigdeli T, Gandal MJ, Daskalakis NP.   +11 more
europepmc   +1 more source

The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia

Advanced Science, EarlyView.
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo, Seong‐Gook Kang, Kunlun Huang, Tao Tong   +3 more
wiley   +1 more source

Failed induction of human labour is associated with an altered myometrial phosphoproteome. [PDF]

Sci Rep
Birchenall KA, Hudson C, Lewis PA, Bahl R, Quinn S, Heesom K, Welsh GI, López Bernal A.   +7 more
europepmc   +1 more source

Stress‐Programmed Immune Niches Fuel TNFR2+ Treg Activation and Drive Neoadjuvant Chemotherapy Resistance in Breast Cancer

Advanced Science, EarlyView.
Single‐cell sequencing reveals stress‐programmed immune states driving TNFα–TNFR2–mediated Treg activation and therapy resistance in breast cancer, while targeting this axis restores antitumor immunity. ABSTRACT The tumor microenvironment (TME) harbors diverse immune cell states that shape therapeutic outcomes in breast cancer.
Zhibo Shao, Xuliren Wang, Han Zhu, Ling Yao, Qi Zhang, Zihan Zhai, Xinyi Lv, Xinyuan Xia, Yi Zhang, Xinya Lu, Xinyi Quan, Jiawen Yang, Xinwei Li, Jieyi Dong, Zhi‐ming Shao, Ruoxi Wang, Bingqiu Xiu, Jiong Wu, Sheng Chen   +18 more
wiley   +1 more source

A computational reference for human genomics analysis in (poly)phenol research.

Food Funct
Treccani M, Ghiretti L, Tosi N, Mignogna C, Minihane AM, Barili V, Del Rio D, Martorana D, Mena P.   +8 more
europepmc   +1 more source

Volumetric analysis of hippocampal subregions in migraine without aura: an exploratory study on mechanisms underlying migraine chronification. [PDF]

J Headache Pain
Feng Q, Chen W, Ke J, Geng D, Xiong X, Dai L, Zhao H, Hu C.   +7 more
europepmc   +1 more source

Mapping cis- and trans-regulatory target genes of human-specific deletions. [PDF]

Nat Commun
Fair T, Pavlovic BJ, Swope D, Castillo OE, Schaefer NK, Pollen AA.   +5 more
europepmc   +1 more source