Results 1 to 10 of about 392,629 (269)

CD28z CARs and Armored CARs [PDF]

open access: yesThe Cancer Journal, 2014
CD19-targeted chimeric antigen receptor (CAR) T cells are currently being tested in the clinic with very promising outcomes. However, limitations to CAR T cell therapy exist. These include lack of efficacy against some tumors, specific targeting of tumor cells without affecting normal tissue and retaining activity within the suppressive tumor ...
Hollie J, Pegram   +2 more
openaire   +2 more sources

Diseño y desarrollo de una arquitectura electrónica bioinspirada para el control de sistemas de asistencia a la locomoción

open access: yesRevista Iberoamericana de Automática e Informática Industrial RIAI, 2023
Este artículo presenta el diseño y desarrollo de una arquitectura electrónica bioinspirada en el sistema motor humano para sistemas de asistencia a la locomoción, como es en el caso de exoesqueletos de asistencia o de rehabilitación.
Gabriel Delgado-Oleas   +4 more
doaj   +1 more source

The Impact of Company Cars on Car Ownership

open access: yesSSRN Electronic Journal, 2022
Amidst the current period of urgent and costly climate abatement policies being implemented, company cars as a fringe benefit receive surprisingly little attention from policy and research, despite evidence showing that they not only result in substantial welfare losses but also in increased car ownership and use.
Börjesson, Maria, Roberts, Chistopher
openaire   +3 more sources

Conventional CARs versus modular CARs [PDF]

open access: yesCancer Immunology, Immunotherapy, 2019
Abstract The clinical application of immune effector cells genetically modified to express chimeric antigen receptors (CARs) has shown impressive results including complete remissions of certain malignant hematological diseases. However, their application can also cause severe side effects such as cytokine release syndrome (CRS) or tumor ...
Feldmann, A.   +5 more
openaire   +2 more sources

CAR race to cancer immunotherapy: from CAR T, CAR NK to CAR macrophage therapy

open access: yesJournal of Experimental & Clinical Cancer Research, 2022
AbstractAdoptive cell therapy with chimeric antigen receptor (CAR) immunotherapy has made tremendous progress with five CAR T therapies approved by the US Food and Drug Administration for hematological malignancies. However, CAR immunotherapy in solid tumors lags significantly behind.
Kevin Pan   +5 more
openaire   +3 more sources

High prevalence of vitamin D insufficiency among elite Spanish athletes: the importance of outdoor training adaptation

open access: yesNutrición Hospitalaria, 2014
Introduction: The discovery of vitamin D muscle receptors in the last few years suggested a significant role in muscle tissue, pointing out athletes as a special group. Specific data are scarce.
Jara Valtueña   +4 more
doaj   +1 more source

ANALYSIS OF ENERGY SAVING AND ENERGY EFFICIENCY ISSUES DURING OPERATION OF THE METRO ROLLING STOCK

open access: yesNauka ta progres transportu, 2016
Purpose.Nowadays a problem of significant power consumption of the rolling stock during its operation is a current issue. In connection with staged electricity rates increase further development of the rail electric transport, including metro rolling ...
A. V. Donchenko   +4 more
doaj   +1 more source

The Driver-Car [PDF]

open access: yesTheory, Culture & Society, 2004
The car has become ubiquitous in late modern society and has become the leading object in the ordinary social relations of mobility. Despite its centrality to the culture and material form of modern societies, the relationship between the car and human beings has remained largely unexplored by sociology.
openaire   +1 more source

STUDY ON ENERGY EXCHANGE PROCESSES IN NORMAL OPERATION OF METRO ROLLING STOCK WITH REGENERATIVE BRAKING SYSTEMS

open access: yesNauka ta progres transportu, 2017
Purpose. The analysis of the existing studies showed that the increasing of energy efficiency of metro rolling stock becomes especially important and requires timely solutions.
A. O. Sulym   +4 more
doaj   +1 more source

Car Design and Car Usage [PDF]

open access: yesProceedings of the Institution of Automobile Engineers, 1919
A Plea for the fuller Appreciation by Car Designers of the limited mechanical Knowledge and engineering Sense of those who buy Cars, together with some Notes of a few Directions in which Design should Be modified with Advantage equally to Manufacturer and User
openaire   +1 more source

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