Results 41 to 50 of about 487,345 (267)

Normal and Anomalous Fluctuation Relations for Gaussian Stochastic Dynamics

, 2012
We study transient work Fluctuation Relations (FRs) for Gaussian stochastic systems generating anomalous diffusion. For this purpose we use a Langevin approach by employing two different types of additive noise: (i) internal noise where the Fluctuation ...
Chechkin, Aleksei V., Klages, Rainer, Lenz, Friedrich   +2 more
core   +1 more source

Recent Developments in FDR [PDF]

, 2012
We describe and report upon various substantial extensions of the CSP refinement checker FDR including (i) the direct ability to handle real-time processes; (ii) the incorporation of bounded model checking technology; (iii) the development of conservative and highly efficient static analysis algorithms for guaranteeing livelock-freedom; and (iv) the ...
Armstrong, P, Goldsmith, M, Lowe, G, Ouaknine, J, Palikareva, H, Roscoe, A, Worrell, J   +6 more
openaire   +3 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Faktor Makroekonomi dan Mikroekonomi dalam Pembiayaan Bermasalah Bank Syariah di Indonesia

Equilibrium: Jurnal Ekonomi Syariah, 2020
Research aims to test the influence of macroeconomic and microeconomic factors in the problem financing of Sharia Bank in Indonesia. The indicators of macroeconomic and microeconomic factors are inflation, BI Rate, CAR and FDR.
Pani Akhiruddin Siregar, Tri Wahyuni, Kadri Bancin   +2 more
doaj   +1 more source

Universality of Fluctuation-Dissipation Ratios: The Ferromagnetic Model [PDF]

, 2005
We calculate analytically the fluctuation-dissipation ratio (FDR) for Ising ferromagnets quenched to criticality, both for the long-range model and its short-range analogue in the limit of large dimension. Our exact solution shows that, for both models, $
Beijnum, Bert-Jan van, Hermens, Hermie, Konstantas, Dimitri, Pawar, Pravin, Wac, Katarzyna   +4 more
core   +6 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

FDR control with adaptive procedures and FDR monotonicity

The Annals of Applied Statistics, 2011
Published in at http://dx.doi.org/10.1214/10-AOAS399 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Zeisel, Amit, Zuk, Or, Domany, Eytan
openaire   +3 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

THE EFFECT OF FINANCIAL PERFORMANCE ON THE PROFITABILITY OF BANK SYARIAH IN INDONESIA THROUGH NET INCOME WITH PATH ANALYSIS

Profit: Jurnal Kajian Ekonomi dan Perbankan Syariah
Penelitian ini bertujuan untuk menentukan pengaruh rasio keuangan CAR, NPF, dan FDR terhadap profitabilitas perbankan syariah di Indonesia dengan rasio Laba Bersih sebagai variabel intervening.
Rizka Mauliddiana, Aufar Fadlul Hady, Clarashinta Canggih   +2 more
doaj   +1 more source