Results 81 to 90 of about 509,208 (305)

The Choice Between Madison and FDR [PDF]

open access: yes, 2008
This exchange is about three clauses that have often been used by the courts since the New Deal to expand federal power: the Commerce Clause, the Necessary and Proper Clause, and the Taxation Clause, from which the spending power has (at least until ...
Barnett, Randy E
core   +1 more source

Multiple testing via $FDR_L$ for large-scale imaging data

open access: yes, 2011
The multiple testing procedure plays an important role in detecting the presence of spatial signals for large-scale imaging data. Typically, the spatial signals are sparse but clustered. This paper provides empirical evidence that for a range of commonly
Fan, Jianqing, Yu, Tao, Zhang, Chunming
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

PROFITABILITY DETERMINANTS OF INDONESIAN ISLAMIC BANKS: FINANCING TO DEPOSIT RATIO AND GOVERNANCE

open access: yesFinansia
This study aimed to thoroughly examine the impact of financing-to-deposit ratio (FDR) on profitability of Islamic commercial banks in Indonesia, with Good Corporate Governance (GCG) acting as an intervening variable.
Tri Wahyudi, Fiesty Utami, Nur Sabrina
doaj   +1 more source

Analisis Faktor-Faktor Yang Mempengaruhi Non Performing Financing (Npf) Di Industri Bank Pembiayaan Rakyat (Bpr) Syariah Di Indonesia

open access: yesAkrual: Jurnal Akuntansi, 2014
The study was conducted to examined and analyzed factors that affect non-performing finance in Islamic Rural Bank Industry in Indonesia. The study used quantitative approach with time series data in the form of Islamic Rural Bank financial report of the ...
Achmad Yasin
doaj   +1 more source

Verification of STAR-Vote and Evaluation of FDR and ProVerif

open access: yes, 2017
We present the first automated privacy analysis of STAR-Vote, a real world voting system design with sophisticated "end-to-end" cryptography, using FDR and ProVerif. We also evaluate the effectiveness of these tools.
Moran, Murat, Wallach, Dan S.
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

The AMR Knowledge Space Game: participatory modeling to address the complexity of antimicrobial resistance

open access: yesScientific Reports
Antimicrobial resistance (AMR) is an urgent and complex global health threat, widely recognized as a silent pandemic that erodes the effectiveness of existing countermeasures and exacerbates vulnerabilities across systems.
Francesca de Rosa   +3 more
doaj   +1 more source

Dependency and false discovery rate: Asymptotics

open access: yes, 2007
Some effort has been undertaken over the last decade to provide conditions for the control of the false discovery rate by the linear step-up procedure (LSU) for testing $n$ hypotheses when test statistics are dependent.
Dickhaus, Thorsten   +2 more
core   +1 more source

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