Results 81 to 90 of about 176,150,519 (294)

Coping strategies tailored to the management of fear of recurrence and adaptation for E‐health delivery: The FoRtitude intervention

, 2017
Fear of recurrence has been well documented among cancer survivors, yet there have been few publications on strategies for coping with this fear. This report describes 3 coping strategies tailored to the management of fear of recurrence and the delivery ...
David Cella, Lynne I. Wagner, David C. Mohr, Wagner, Lynne I, Duffecy, Jenna, Frank Penedo, Jenna Duffecy, Penedo, Frank, Cella, David, Mohr, David C   +9 more
core   +1 more source

Fear of Cancer Recurrence and Inhibited Disclosure: Testing the Social-Cognitive Processing Model in Couples Coping With Breast Cancer

, 2020
Over the first year of breast cancer survivorship, when patients or their intimate partners felt unable to share cancer-related concerns with one another, they reported higher levels of fear of cancer ...
Siegel, Scott D, Otto, Amy K, LoSavio, Stefanie T, Perndorfer, Christine, Laurenceau, Jean-Philippe, Soriano, Emily C   +5 more
core   +1 more source

Selective Attention and Fear of Cancer Recurrence in Breast Cancer Survivors

Annals of Behavioral Medicine, 2014
Anxious people show an attentional bias towards threatening information.It was investigated whether an attentional bias exists for cancer-related stimuli in breast cancer survivors and if different levels of fear of cancer recurrence would lead to different patterns of selective attention.Breast cancer survivors with high (n = 35) and low (n = 32) fear
Custers, J.A.E., Becker, E.S., Gielissen, M.F.M., Laarhoven, H.W.M. van, Rinck, M., Prins, J.B.   +5 more
openaire   +5 more sources

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

A qualitative study evaluating experiences of a lifestyle intervention in men with prostate cancer undergoing androgen suppression therapy [PDF]

, 2012
Background - The severe iatrogenic hypogonadal state induced by medical castration used for treatment of prostate cancer is associated with adverse effects including fatigue, increased fracture risk, and a decrease in skeletal muscle function, which ...
Saxton John M, Nanton Veronica, Helen Crank, Rosario, DJ, Sohanpal, R, Bourke, Liam, John M Saxton, Crank, H., Saxton, John, Bourke Liam, Crank, Helen, Liam Bourke, Saxton, J.M., Nanton, Veronica, Crank Helen, Rosario, D.J., Saxton, John M., Ratna Sohanpal, Sohanpal, Ratna, Saxton, JM, Nanton, V., Bourke, L, Nanton, V, Rosario, Derek J., Sohanpal Ratna, Rosario Derek J, Rosario, D, Derek J Rosario, Veronica Nanton, Crank, H, Bourke, L., Sohanpal, R.   +31 more
core   +2 more sources

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

The interconnectedness of fear of cancer recurrence components: A network approach.

Health Psychology
While nearly 60% of cancer survivors report a heightened fear of cancer recurrence (FCR), not all of them experience functional impairment and want professional psychological care. We applied the network approach to study how different components of FCR (symptoms, triggers, perceived risk, and coping strategies) are interconnected to both FCR severity ...
Melanie P. J. Schellekens, Yvonne L. Luigjes-Huizer, Allan Ben Smith, José A. E. Custers, Sébastien Simard, Sophie Lebel, Marije L. van der Lee   +6 more
openaire   +3 more sources

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

The relationship between illness representations , risk perception and fear of cancer recurrence in breast cancer survivors [PDF]

, 2017
Fear of cancer recurrence, although distinct from distress continues to be under-evaluated, captured, or treated when standard distress scales are used to assess concerns of cancer survivors. We tested a model assessing the association of demographic and
Janz, Nancy K., Katapodi, Maria C., Zikmund‐fisher, Brian J., Northouse, Laurel, Zikmund-Fisher, Brian J., Freeman-Gibb, Laurie A., Freeman‐gibb, Laurie A., Freeman-Gibb LA, Zikmund-Fisher BJ, Katapodi MC, Janz NK, Northouse L   +11 more
core   +1 more source