Results 101 to 110 of about 1,635,532 (265)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

South Valley Incorporation Feasibility Study: Presentation to the South Valley Community

, 2008
Revised "...with minor corrections as noted, October 2008"Slide presentation summarizing the findings of the South Valley incorporation feasibility study.
Reynis, Lee A.
core  

Patient and provider preferences for long-acting TB preventive therapy

IJTLD Open
BACKGROUND: Tuberculosis preventive therapy (TPT) is critical for TB elimination but is underutilised. Long-acting (LA) TPT can potentially improve linkage to care, treatment adherence and outcomes.
M. Vermeulen, K.K. Scarsi, R. Furl, H. Sayles, M.J. Anderson, S. Valawalkar, A. Kadam, S.R. Cox, V. Mave, M. Barthwal, C. Schutz, A. Ward, J. Dountio Ofimboudem, G. Meintjes, S. Rannard, A. Owen, S. Swindells, on behalf of the LONGEVITY consortium   +17 more
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

A virtual reality-based self-guided training on identification of negative automatic thoughts in healthy adults: a mixed-methods feasibility study

Frontiers in Psychiatry
BackgroundCognitive restructuring (CR) is an evidence-based psychological technique for depression. However, face-to-face CR is not easily accessible. Digital CR interventions often overlook the difficulties individuals experiencing depression encounter ...
Bixi Yang, Chenxi Liao, Yuqing Yang, Yuqing Yang, Binbin Shi, Caidi Zhang, Chunbo Li, Chunbo Li, Chunbo Li   +8 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Dairy digester feasibility study summary report

, 2010
Anaerobic digestion of dairy manure is a proven technology with a long history, immediately available for commercial applications from a number of qualified vendors.

core  

The Safety, Acceptability, and Feasibility of Single-Dose Rifampicin as Post-Exposure Chemoprophylaxis for Contacts of Leprosy Patients in Togo: A Mixed-Method Sequential Explanatory Study

Tropical Medicine and Infectious Disease
The World Health Organization is encouraging countries to include contact screening and single-dose rifampicin administration as preventive chemotherapy for contacts of leprosy patients in their leprosy control activities.
Akila Wimima Bakoubayi, Falapalaki Haliba, Wendpouiré Ida C. Zida-Compaore, P’tanam P’kontème Bando, Yao Rodion Konu, Abissouwèssim Egbare Tchade, Kodjo Akpadja, Kamevor Alaglo, Maweke Tchalim, P’niwè Patchali, Yaovi Djakpa, Komi Amekuse, Piham Gnossike, Denis A. Yawovi Gadah, Christa Kasang, Didier Koumavi Ekouevi   +15 more
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Risk Assessment in Economic Feasibility Analysis: The Case of Ethanol Production in Texas [PDF]

The objective of this study is to demonstrate the benefits of quantifying the economic viability of a proposed agribusiness under risk relative to a feasibility study which ignores risk.
Klose, Steven L., Anderson, David P., Herbst, Brian K., Outlaw, Joe L., Gill, Robert Chope, II, Richardson, James W.   +5 more
core