Results 131 to 140 of about 708,034 (258)

Design and Evaluation of User-Centered Exergames for Patients With Multiple Sclerosis: Multilevel Usability and Feasibility Studies. [PDF]

JMIR Serious Games, 2021
Schättin A, Schättin A, Häfliger S, Meyer A, Früh B, Böckler S, Hungerbühler Y, de Bruin ED, Frese S, Steinlin Egli R, Götz U, Bauer R, Martin-Niedecken AL.   +12 more
europepmc   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Jointly assessing multiple endpoints in pilot and feasibility studies. [PDF]

Stat Methods Med Res
Montgomery RN, Bodde AE, Vidoni ED.
europepmc   +1 more source

Small studies, big decisions: the role of pilot/feasibility studies in incremental science and premature scale-up of behavioral interventions. [PDF]

Pilot Feasibility Stud, 2021
Beets MW, von Klinggraeff L, Weaver RG, Armstrong B, Burkart S.   +4 more
europepmc   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Stakeholder Perspectives on Early Feasibility Studies for Digital Health Technologies in the European Union: Qualitative Interview Study. [PDF]

J Med Internet Res
Peseke M, Michaelis I, Kayembe OT, Geraghty M, McDonnell A, Zurlo FL, Oftring ZS, Martelli N, Melvin T, Kuhn S.   +9 more
europepmc   +1 more source

Lessons learned from eight teams: The value of pilot and feasibility studies in self-management science. [PDF]

Appl Nurs Res, 2021
Danesh V, Zuñiga JA, Timmerman GM, Radhakrishnan K, Cuevas HE, Young CC, Henneghan AM, Morrison J, Kim MT.   +8 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Pilot and feasibility studies in ophthalmology: fundamental keys to success. [PDF]

Eye (Lond)
Nanji K, Phillips M, Thabane L, Tham YC, Wong TY, Steel DH, Munk MR, Wykoff CC, Chaudhary V, Retina Evidence and Trials INternational Alliance (R.E.T.I.N.A.) Study Group.   +9 more
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source