Results 181 to 190 of about 806,359 (300)

Jointly assessing multiple endpoints in pilot and feasibility studies. [PDF]

Stat Methods Med Res
Montgomery RN, Bodde AE, Vidoni ED.
europepmc   +1 more source

Lessons learned from eight teams: The value of pilot and feasibility studies in self-management science. [PDF]

Appl Nurs Res, 2021
Danesh V, Zuñiga JA, Timmerman GM, Radhakrishnan K, Cuevas HE, Young CC, Henneghan AM, Morrison J, Kim MT.   +8 more
europepmc   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Pilot and feasibility studies in ophthalmology: fundamental keys to success. [PDF]

Eye (Lond)
Nanji K, Phillips M, Thabane L, Tham YC, Wong TY, Steel DH, Munk MR, Wykoff CC, Chaudhary V, Retina Evidence and Trials INternational Alliance (R.E.T.I.N.A.) Study Group.   +9 more
europepmc   +1 more source

Dairy digester feasibility study summary report

, 2010
Anaerobic digestion of dairy manure is a proven technology with a long history, immediately available for commercial applications from a number of qualified vendors.

core  

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

Forty years on, why are we still publishing extracorporeal carbon dioxide removal feasibility studies? [PDF]

Crit Care
Cove ME, Combes A, P Hilty M.
europepmc   +1 more source

Correction: Design and Evaluation of User-Centered Exergames for Patients With Multiple Sclerosis: Multilevel Usability and Feasibility Studies. [PDF]

JMIR Serious Games, 2021
Schättin A, Häfliger S, Meyer A, Früh B, Böckler S, Hungerbühler Y, de Bruin ED, Frese S, Steinlin Egli R, Götz U, Bauer R, Martin-Niedecken AL.   +11 more
europepmc   +1 more source

Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi, Sola Al Ghazal, Salem Hannoun, Medhat A. Siddik, Nour M. Najjar, Jim Dagher, Joseph Abboud, Myriam G. Semaan, Samia J. Khoury   +8 more
wiley   +1 more source

Methodological standards in the design and reporting of pilot and feasibility studies in emergency medicine literature: a systematic review. [PDF]

BMJ Open
Ruangsomboon O, Lima JP, Eltorki M, Worster A.   +3 more
europepmc   +1 more source