Results 131 to 140 of about 6,356,098 (354)
Emerging role of ARHGAP29 in melanoma cell phenotype switching
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Background: Breast cancer remains a critical public health problem worldwide and is a leading cause of cancer-related mortality. Optimizing clinical outcomes is contingent upon the early and precise detection of malignancies.
Nazmul Ahasan Maruf +2 more
doaj +1 more source
Federated Automated Feature Engineering
Preliminary ...
Overman, Tom, Klabjan, Diego
openaire +2 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Enhancing Security in Airline Ticket Transactions: A Comparative Study of SVM and LightGBM
Fraudulent online payment operations represent a persistent challenge in digital commerce, particularly in sectors like air travel, where credit and debit card payments dominate.
César Gómez Arnaldo +3 more
doaj +1 more source
Engineering knowledge requirements for sand and dust on Mars [PDF]
The successful landing of human beings on Mars and the establishment of a permanent outpost there will require an understanding of the Martian environment by the engineers.
Kaplan, D. I.
core +1 more source
Feature-Based Virtual Engineering [PDF]
In this paper the concept of Feature-based Virtual Engineering is presented as an approach to integrated product development. The focus of the paper is on presenting the current state of the development of a feature-based parametric representation for product semantics including a concept for creating and maintaining application specific views on the ...
openaire +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Accurate estimation of State of Health (SOH) is pivotal for managing the lifecycle of lithium-ion batteries (LIBs) and ensuring safe and reliable operation in electric vehicles (EVs) and energy storage systems.
Leila Amani +2 more
doaj +1 more source

