Results 171 to 180 of about 524,719 (351)

Gear Degradation Study Using Statistical Time Features and Shallow Neural Networks

IEEE Access
Gears are widely recognized as crucial components for power connections and transmission owing to their substantial loading capacity, transmission efficiency, and consistent power output.
Shahil Kumar, Krish Kumar Raj, Maurizio Cirrincione, Giansalvo Cirrincione, Rahul Ranjeev Kumar   +4 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Intelligent feature based resource selection and process planning

, 2012
Lien vers la version éditeur: https://www.inderscience.com/books/index.php?action=record&rec_id=755&chapNum=3&journalID=1022&year=2010This paper presents an intelligent knowledge-based integrated manufacturing system using the STEP feature-based ...
MARTIN, Patrick, ZIZ, William, SIADAT, Ali, SADEGHI, Samira, SADEGHI, Mohsen   +4 more
core  

Short-Term Water Demand Forecasting Using Machine Learning Approaches in a Case Study of a Water Distribution Network Located in Italy

Engineering Proceedings
Machine learning’s application in short-term water demand forecasting remains a pivotal area of research in water distribution system studies. This investigation reveals a distinctive distribution pattern for the daily demand following dataset ...
Qidong Que, Jinliang Gao, Wenyan Wu, Huizhe Cao, Kunyi Li, Hanshu Zhang, Yi He, Rui Shen   +7 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Feature-Oriented Modelling Using Event-B

Event-B is a formal method for specification and verification of reactive systems. Its Rodin toolkit provides comprehensive support for modelling, refinement and analysis using theorem proving, animation and model checking.
Snook, Colin, Gondal, Ali, Butler, Michael, Poppleton, Mike   +3 more
core  

A knowledge‐based materials descriptor for compositional dependence of phase transformation in NiTi shape memory alloys

Materials Genome Engineering Advances
This study presents ∆τ, a novel descriptor that captures the compositional dependence of phase transformation temperature (Ap) in NiTi‐based shape memory alloys (SMAs).
Cheng Li, Qingkai Liang, Yumei Zhou, Dezhen Xue   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Generalising feature interactions in email [PDF]

, 2003
We report on a property-based approach to feature interaction analysis for a client-server email system. The model is based upon Hall's email model presented at FIW'00, but the implementation is at a lower level of abstraction, employing non-determinism ...
Calder, M., Miller, A.
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source