Results 161 to 170 of about 524,719 (351)

Incorporating Reverse Engineering Methodology into Engineering Curricula

, 2012
Wanamaker, Trevor W., M.S., Purdue University, May 2012. Incorporating Reverse Engineering Methodology into Engineering Curricula. Major Professor: Craig L. Miller.
Wanamaker, Trevor, Wanamaker, Trevor W
core  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Toward compound fault diagnosis via EMAGAN and large kernel augmented few-shot learning

Frontiers in Mechanical Engineering
Bearings are essential in machinery. Damage to them can cause financial losses and safety risks at industrial sites. Therefore, it is necessary to design an accurate diagnostic model.
Wenchang Xu, Zhexian Zhang, Zhijun Wang, Tianao Wang, Zijian He, Shijie Dong   +5 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Deep Learning for Marine Vehicles Parking Availability: A ResNet50-Based Deep Feature Engineering Model

In this research, our essential objective is to evaluate the availability of parking spaces within port/marine/fisher shelters employing a novel computer vision-based approach.
Cambay, Veysel Yusuf, Hajiyev, Rena, Gurturk, Mert, Tuncer, Turker, Hajiyeva, Rena, Hafeez-Baig, Abdul, Dogan, Sengul   +6 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Directed Lobish-based explainable feature engineering model with TTPat and CWINCA for EEG artifact classification

Background and Objective: Electroencephalography (EEG) signals are crucial to decipher various brain activities. However, these EEG signals are subtle and contain various artifacts, which can happen due to various reasons.
Mungen, Bulent, Baygin, M, Tasci, Burak, Tuncer, T, Baygin, Mehmet, Barua, Prabal Datta, Dogan, S, Tuncer, Turker, Barua, PD, Dogan, Sengul, Tasci, Irem, Acharya, U. R., Acharya, UR, Mungen, B, Tasci, I, Tasci, B, Acharya, U.R.   +16 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Predictive Modeling of Earthquakes in Los Angeles With Machine Learning and Neural Networks

IEEE Access
Earthquakes pose a significant threat to urban areas, necessitating accurate forecasting models to mitigate their impact. This study focuses on earthquake forecasting in Los Angeles, a region with high seismic activity and limited research.
Cemil Emre Yavas, Lei Chen, Christopher Kadlec, Yiming Ji   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source