Results 111 to 120 of about 3,899,370 (385)
Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston+7 more
wiley +1 more source
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt+8 more
wiley +1 more source
Purification tags markedly affect self‐aggregation of CPEB3
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito+6 more
wiley +1 more source
Application of Fast Kurtosis Spectrum in Fault Feature Extraction of Compound Planetary Gear
Fast kurtosis specturm has fast detection ability for transient impulse signal and is widely used in fault feature extraction of rotating machinery. A process of extracting mechanical fault feature based on fast computation of kurtogram is proposed and ...
Wu Shoujun Feng Fuzhou Wu Chunzhi Ding Chuang
doaj
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever+1 more
wiley +1 more source
Pneumonia Detection Using CNN based Feature Extraction
Pneumonia is a life-threatening infectious disease affecting one or both lungs in humans commonly caused by bacteria called Streptococcus pneumoniae. One in three deaths in India is caused due to pneumonia as reported by World Health Organization (WHO ...
Dimpy Varshni+4 more
semanticscholar +1 more source
Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren+16 more
wiley +1 more source
Micro-expression (ME) is spontaneous, rapid, and subtle facial mechanism that can reveal the concealed emotions. However, the short duration, low motion intensity, and small dataset of MEs make the extraction and learning of features from ME samples more
Peiyun Xue+3 more
doaj +1 more source
A Set-based Approach for Feature Extraction of 3D CAD Models [PDF]
Feature extraction is a critical technology to realize the automatic transmission of feature information throughout product life cycles. As CAD models primarily capture the 3D geometry of products, feature extraction heavily relies on geometric information.
arxiv